Columbia University Irving Medical Center

Projects

Projects per year 1984 2009 2022 2023 2024 2028

• 3 Not started
• 133 Active
• 492 Finished

Projects per year

Search results

• Finished

  Drug Mechanism of Action-based targeting of tumor subpopulations

  Califano, A. A. (PI)

  9/1/23 → 8/31/24

  Project: Research project

  • Immune Checkpoints 100%
  • Small Molecule 100%
  • Oncogene 100%
  • Drug Mechanism 100%
  • Mouse Model 100%

• Outreach Core

  Murray, D. D. (PI)

  9/1/23 → 8/31/24

  Project: Research project

  • Outreach 100%
  • Therapy 100%
  • Systems Biology 36%
  • Secondary Schools 36%
  • Scientists 27%

• Advanced Single Cell Technology Innovation Core

  Sims, P. P. A. (PI)

  9/1/23 → 8/31/24

  Project: Research project

  • RNA Sequencing 100%
  • Malignant Neoplasm 100%
  • RNA 100%
  • Analytic Method 50%
  • Neoplasm 50%

• Project 3: A Transdisciplinary Approach to Increasing Phytonutrients in New Mexican Diets: A Kitchen-to-Lab-to-Table Model

  Greenlee, H. A. (PI)

  9/1/23 → 8/31/24

  Project: Research project

  • Phytonutrients 100%
  • Chlorophyll 100%
  • Carotenoid 100%
  • Diet Quality 75%
  • Tocopherol 50%

• Uncovering novel mechanisms and potential therapeutic targets for IgA vasculitis through GWAS and systems-level analysis of regulatory networks.

  Liu, L. L. (PI)

  8/24/23 → 5/31/24

  Project: Research project

  • IgA Vasculitis 100%
  • Genome Wide Association Study 100%
  • Regulatory Network 100%
  • Genetics 100%
  • Immunoglobulin A 100%

• Health Disparities in Hospice in Nursing Homes

  Stone, P. W. (PI), Dick, A. W. (CoPI) & Dhingra, L. (CoPI)

  8/23/23 → 6/30/24

  Project: Research project

  • Nursing Home 100%
  • Health Disparity 100%
  • Hospice Care 40%
  • Terminal Care 20%
  • End of Life Care 20%

• Elucidating the Consequences of Chromosome 3 Arm Aneuploidies in Squamous Cell Carcinoma

  Taylor, A. A. M. (PI)

  8/21/23 → 7/31/24

  Project: Research project

  • Aneuploidy 100%
  • Chromosome 3 100%
  • Chromosome Arm 50%
  • Chromosome 3q 50%
  • Carcinogenesis 33%

• Architecture, dynamics and regulation of erythrocyte ankyrin-1 complexes

  Clarke, O. O. B. (PI)

  8/20/23 → 7/31/24

  Project: Research project

  • Dynamics 100%
  • Ankyrin 100%
  • Band 3 30%
  • Membrane Protein 30%
  • Transmembrane Protein 30%

• Development and application of a quantitive model for HIV-1 transcriptional activation driven by TAR RNA conformational dynamics

  Al-hashimi, H. H. M. (PI), Herschlag, D. D. (CoPI) & Goff, S. S. P. (CoPI)

  8/17/23 → 7/31/24

  Project: Research project

  • Dynamics 100%
  • Human Immunodeficiency Virus 1 100%
  • Transcription Initiation 100%
  • RNA 100%
  • Transactivation 100%

• NY Community-Hospital-Academic Maternal Health Equity Partnerships (NY-CHAMP)

  Reddy, U. U. (PI), Rodriguez, E. E. (CoPI), Li, G. G. (CoPI), Taylor, J. J. Y. (CoPI), Hall, K. K. S. (CoPI), Osborne, L. L. M. (CoPI), Dorval-moller, M. M. (CoPI), Safford, M. M. M. (CoPI), Brown, S. S. (CoPI) & St. Clair, V. V. (CoPI)

  8/17/23 → 7/31/24

  Project: Research project

  • Maternal Welfare 100%
  • Health Disparity 12%
  • Patient Care 12%
  • Health Care Cost 12%
  • Cognitive Behavioral Therapy 12%

• Non-APOL1 genetic factors and kidney transplant outcomes

  Kiryluk, K. K. (PI)

  8/15/23 → 5/31/24

  Project: Research project

  • Heredity 100%
  • Kidney Graft 100%
  • Kidney Transplantation 100%
  • Genetics 100%
  • Genetic Determinism 100%

• Investigating the role of long-term latent herpes simplex virus infection on APOE4-associated Alzheimer's disease pathogenesis

  Nuriel, T. T. (PI) & Cliffe, A. A. R. (CoPI)

  8/15/23 → 4/30/24

  Project: Research project

  • Virus Infection 100%
  • Human Alphaherpesvirus 1 100%
  • Herpes Simplex Virus 100%
  • Alzheimer's Disease 100%
  • Infection 83%

• Impact of Environmental Exposures on Lung Immunity over Age

  Ural, B. B. (PI)

  8/15/23 → 4/30/24

  Project: Research project

  • Environmental Exposure 100%
  • Macrophage 100%
  • Lung 100%
  • Diseases 100%
  • Lymph Node 71%

• Molecular Mechanisms of MDS pathogenesis with aging

  Kousteni, S. S. (PI)

  8/15/23 → 4/30/24

  Project: Research project

  • Nucleoporin 100%
  • Stem Cell 37%
  • Hematopoiesis 12%
  • NUP98 12%
  • Molecular Genetics 12%

• Identification of smooth muscle cell genes causal in atherosclerotic plaque stability and cardiovascular disease risk

  Reilly, M. M. P. (PI) & Saleheen, D. D. (CoPI)

  8/10/23 → 6/30/24

  Project: Research project

  • Mouse Model 100%
  • Single Nucleotide Polymorphism 66%
  • Pleiotropy 66%
  • RNA 66%
  • Genetics 33%

• Decoding the Interferome by Mapping Genetic Interactions in Human Tissue

  Gaudet, R. R. G. (PI)

  8/10/23 → 7/31/24

  Project: Research project

  • Interferon-Stimulated Gene 100%
  • Human Tissue 100%
  • Gene Interaction 100%
  • Immunocompetent Cell 50%
  • Interferon Type I 25%

• Role of long non-coding RNAs in exosome biogenesis

  Momen Heravi, F. F. (PI)

  8/10/23 → 7/31/24

  Project: Research project

  • Biogenesis 100%
  • Long Non-Coding RNA 100%
  • Exosome 100%
  • Long Noncoding RNA 66%
  • Cell Communication 33%

• Insulin regulation of hepatic transport

  Haeusler, R. R. A. (PI)

  8/9/23 → 5/31/24

  Project: Research project

  • Bile Acid 100%
  • Bile 25%
  • Hepatocyte 25%
  • Insulin Resistance 12%
  • Public Health 12%

• SEARCH: SMS Electronic Adolescent Reminders for Completion of HPV vaccination- Uganda

  Stockwell, M. S. (PI) & Kitaka, S. B. (CoPI)

  8/1/23 → 7/31/24

  Project: Research project

• 2/4-The INTEGRATE Study: Evaluating INTEGRATEd care to Improve Biopschosocial Outcomes of Early Liver Transplantation for Alcohol-Associated Liver Disease

  Verna, E. E. C. (PI)

  8/1/23 → 7/31/24

  Project: Research project

• Engineered Hydrogel Elucidates the Contribution of ECM Stiffness to Barrett's Esophagus Pathogenesis

  Cruz Acuña, R. R. (PI)

  8/1/23 → 4/30/24

  Project: Research project

  • Esophagus 100%
  • Rigidity 100%
  • Barrett Esophagus 100%
  • Metaplasia 20%
  • Organoid 20%

• Clearance of Dead Hepatocytes by Liver Macrophages in NASH

  Shi, H. H. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Macrophage 100%
  • Nonalcoholic Fatty Liver 100%
  • Hepatocyte 100%
  • Steatohepatitis 100%
  • Efferocytosis 22%

• Broad spectrum inhibitors of paramyxovirus envelope proteins

  Moscona, A. A. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Envelope Protein 100%
  • Paramyxoviridae 100%
  • Peptides 100%
  • Antivirus Agent 75%
  • Lipopeptide 75%

• 3D Culture Models of Partial-EMT and Its Regulation in Oral Cavity Squamous Cell Carcinoma

  Parikh, A. A. S. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Oral Cavity 100%
  • Epithelial Mesenchymal Transition 100%
  • Squamous Cell Carcinoma 100%
  • TGFBI 100%
  • Growth Factor 77%

• Genetic and neuroanatomical basis of neuropsychiatric symptoms in Alzheimer's disease in populations of diverse ancestry

  Reitz, C. C. (PI), Huey, E. E. D. (CoPI) & Beecham, G. G. W. (CoPI)

  8/1/23 → 7/31/24

  Project: Research project

  • Genetics 100%
  • Genomics 50%
  • Genetic Architecture 25%
  • FUS 25%
  • Genetic Risk 25%

• Impact of nucleotide metabolism on bacterial clearance

  Riquelme Colet, S. S. A. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Dihydroorotate Dehydrogenase 100%
  • Bacterial Clearance 100%
  • Nucleotide Metabolism 100%
  • Airway 100%
  • Infectious Agent 80%

• Dissecting the synaptic and circuit mechanisms underlying olfactory-driven social behavior

  Rodriguez, E. E. J. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Spectrum Disorder 100%
  • Social Behavior 100%
  • Behavior (Neuroscience) 100%

• Transcriptional regulation of urothelial differentiation and cell type specification during homeostasis and regeneration

  Mendelsohn, C. C. L. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Homeostasis 100%
  • Urology 100%
  • Urinary Tract Infection 100%
  • Regeneration 100%
  • Lower Urinary Tract Symptom 50%

• Human genetic approaches to lower urinary tract phenotypes

  Gharavi, A. A. G. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Human Genetics 100%
  • Urinary Tract 100%
  • Vesicoureteral Reflux 100%
  • Genome-Wide Association Study 100%
  • Genetic Approach 100%

• Opportunities Fund Management Core

  Amundson, S. S. A. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Progress Report 100%
  • Pilot Project 100%
  • Translational Research 100%
  • Review Process 50%
  • Standard Operating Procedure 50%

• Biostatistics Core

  Shuryak, I. I. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Biological System 100%
  • Dose Rate 100%
  • Design of Experiments 100%
  • Learning System 100%
  • Transcriptomics 100%

• Irradiation & Dosimetry Core

  Garty, G. G. Y. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Dosimetry 100%
  • Caesium-137 28%
  • in Vivo Dosimetry 14%
  • Ex Vivo 14%
  • Chest 14%

• Animal Core

  Ponnaiya, B. B. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Transgenic Mouse 100%
  • Biological Marker 100%
  • Cesium 137 100%
  • Lung Disease 100%
  • Blood Cell Count 100%

• Nuclear envelope and predisposition to hepatic neoplasia

  Shin, J.-Y. J. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Isoform 100%
  • Nuclear Membrane 100%
  • Nuclear Pore 100%
  • Hepatocyte 66%
  • Carcinogenesis 33%

• Deciphering the mechanism of non-canonical cell cycle entry

  Yang, H. W. H. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Cyclin Dependent Kinase 6 100%
  • Cyclin Dependent Kinase 4 100%
  • Cell Cycle 100%
  • Cyclin-Dependent Kinase 6 56%
  • Cyclin-Dependent Kinase 4 56%

• CE19-001, The Columbia Center for Injury Science and Prevention (CCISP)

  Branas, C. C. C. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Education Program 100%
  • Injury Prevention 100%

• Microbial Genomics Biomedical Core

  Uhlemann, A.-C. A. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Microbial Genomics 100%
  • Urinary Tract Infection 100%
  • Biorepository 33%
  • Urology 25%
  • Microbiome 18%

• Administrative Core

  Brenner, D. D. J. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Mass Casualty 100%
  • Radiation Exposure 100%
  • Decision Making 100%
  • Administrative Structure 100%
  • Decision Making Management 50%

• Rapid Non-invasive Radiation Biodosimetry through Metabolomics

  Fornace, A. A. J. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Metabolomics 100%
  • Biological Marker 100%
  • Radiation Exposure 33%
  • Animal Models 25%
  • Lung Injury 16%

• Administrative Core

  Mendelsohn, C. C. L. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Urinary Tract Infection 100%
  • Urinary System 75%
  • Urology 75%
  • Microbiome 75%
  • Urinary Tract 50%

• A Novel Metabolic Pathway Regulates Urinary Tract Infections in the Bladder

  Barasch, J. J. M. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • Metabolism 100%
  • Bladder 100%
  • Urinary Tract Infection 100%
  • Heme 100%
  • Urinary Tract 100%

• The role of T cells in tendon healing

  Huang, A. A. H. (PI)

  8/1/23 → 7/31/24

  Project: Research project

  • T Cell 100%
  • Tendon Healing 100%
  • Tendon Injury 66%
  • T Lymphocyte Subpopulation 66%
  • Tenocyte 66%

• Hepatic Rap1a in cholesterol homeostasis

  Ozcan, L. L. (PI)

  8/1/23 → 6/30/24

  Project: Research project

  • Proprotein Convertase 9 100%
  • Lipoprotein 62%
  • Statin (Protein) 62%
  • Hydroxymethylglutaryl Coenzyme A Reductase Inhibitor 25%
  • Lipoprotein Receptor 12%

• Hypothalamic lipid signaling in metabolism regulation

  Diano, S. S. (PI)

  8/1/23 → 4/30/24

  Project: Research project

  • Lipid Signaling 100%
  • Metabolic Pathway 100%
  • Sphingosine 1 Phosphate 100%
  • Sphingosine-1-Phosphate 100%
  • Metabolic Regulation 100%

• STK25 phosphorylates PRKAR1A to regulate PKA signaling

  Fine, B. B. M. (PI)

  8/1/23 → 6/30/24

  Project: Research project

  • Protein Kinase A 100%
  • PRKAR1A 100%
  • Cyclic AMP Dependent Protein Kinase 100%
  • Kinase 85%
  • Phosphotransferase 85%

• New therapeutic approaches in clonal hematopoiesis and atherosclerosis

  Tall, A. A. R. (PI)

  8/1/23 → 5/31/24

  Project: Research project

  • Atherosclerosis 100%
  • Hematopoiesis 100%
  • Macrophage 45%
  • Inflammasome 45%
  • Efferocytosis 27%

• Leveraging CRISPR RNA-guided DNA Transposases for Gene Insertion at the CFTR Locus

  King, R. R. T. (PI)

  7/20/23 → 9/30/23

  Project: Research project

  • RNA 100%
  • Gene Insertion 100%
  • CRISPR 100%
  • Transposase 100%
  • Cystic Fibrosis 100%

• Understanding the antiviral roles of acellular RNA quality control pathway

  Steckelberg, A.-L. A. (PI)

  7/15/23 → 5/31/24

  Project: Research project

  • Nonsense-Mediated Decay 100%
  • RNA 100%
  • Quality Control 100%
  • Nonsense Mediated mRNA Decay 100%
  • Viral Disease 31%

• Social Connectedness and Health among Gender Minority People of Color

  Bockting, W. W. O. (PI)

  7/15/23 → 12/31/23

  Project: Research project

  • Minority Stress 100%
  • Social Connectedness 100%
  • Connectedness 25%
  • Perceived Social Support 25%
  • Social Support 25%

• Dental-Biomedical Engineering Scholars Training (D-Best) Program

  Wadhwa, S. S. (PI)

  7/1/23 → 6/30/24

  Project: Research project