Imaging How a Neuron Computes

The eleven laboratories have continued the development of new imaging methodologies aimed at the scientific goal of understanding how neurons compute with great success. In particular, we have had major publications in the stimulated Raman scattering (Wei and Yuste), methods for methods for demixing spatiotemporal calcium imaging data (Paninski) and their application to multiplane imaging in vivo (Yuste) and sesrial EM studies (Lichtman). We also have continued to develop nanodiamond voltage sensing, atomic force microscopy and SPAD. We are continuing on course and do not expect any changes to the team or overall direction as we move forward.