Neuropsychiatric symptoms in children and adolescents with Lyme disease

Recent studies have shown that some children can develop sudden onset neuropsychiatric symptoms after infections. Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infections (PANDAS) includes symptoms such as obsessive compulsive disorder, anxiety, tics, and eating disorders. In this study, children and adolescents with acute onset neuropsychiatric symptoms will be studied to determine whether there is a connection with diagnosis of Lyme and other tickborne disease. Psychiatric and cognitive testing along with clinical evaluation, biorepository collection and biomarker analysis will also be carried out.