Columbia University

Projets

Projets par année 1973 1984 1995 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2030

• 7 Non entamé
• 293 Actif
• 1717 Terminé

Projets par année

Rechercher les résultats

• Terminé

  Structure and mechanism of pendrin and the mutations that cause Pendred's Syndrome

  Quick, M. M. (PI) & Zhou, M. (CoPI)

  9/1/23 → 5/31/24

  Projet

  • Pendrin 100%
  • Pendred Syndrome 100%
  • Syndrome 21%
  • Niflumic Acid 14%
  • Binding Site 14%

• Methods for inferring and analyzing gene regulatory networks using single-cell multiomics and spatial genomics data

  Hou, W. W. (PI)

  9/1/23 → 8/31/24

  Projet

  • Gene Control 100%
  • Gene Regulatory Network 100%
  • Genomics 100%
  • Transcriptomics 22%
  • Epigenomics 22%

• Creating Resources Uplifting Nutrition, Culture, and Health at Lunch (CRUNCH Lunch)

  Koch, P. (PI)

  9/1/23 → 7/31/24

  Projet

  • Mathematics 100%
  • School Lunch 100%
  • Nutrition 100%
  • School Meal 25%
  • Nutrition Education 25%

• Immune and transcriptomic biomarkers of progressive oral premalignant lesions

  Momen Heravi, F. F. (PI)

  9/1/23 → 8/31/24

  Projet

  • Biological Marker 100%
  • Leukoplakia 100%
  • Transcriptomics 100%
  • Disease 100%
  • Immunity 100%

• Immune, hormonal, and muscle mitochondrial determinants of recovery in Acute Respiratory Distress Syndrome survivors

  Baldwin, M. R. (PI)

  9/1/23 → 7/31/24

  Projet

  • Acute Respiratory Distress Syndrome 100%
  • Immunity 100%
  • Adult Respiratory Distress Syndrome 100%
  • Biological Marker 18%
  • Mitochondrial Disorder 18%

• Project 1: Identifying and optimizing monogenetic risk prediction for autism in newborns

  Chung, W. W. K. (PI)

  9/1/23 → 8/31/24

  Projet

  • Genetics 100%
  • Genetic Divergence 100%
  • Genetic Risk 100%
  • Genomics 100%
  • Urban Population 66%

• Examining Individuals' Exposure to Alcohol Environments Using Novel Responsive Buffers

  Mehranbod, C. (PI)

  9/1/23 → 8/31/24

  Projet

  • Risk Factor 100%
  • Systematic Review 100%
  • Research and Development 100%
  • Alcohol Consumption 100%
  • Individual Level 100%

• Physical activity, physical function, and frailty in relation to cognitive impairment and AD/ADRD biomarkers in DPPOS

  Palta, P. (PI)

  9/1/23 → 8/31/24

  Projet

  • Biological Marker 100%
  • Physical Activity 100%
  • Frailty 100%
  • Cognitive Defect 100%
  • Cognitive Disorders 100%

• Biostatistics and Data Infrastructure core

  Temprosa, M. M. (PI)

  9/1/23 → 8/31/24

  Projet

  • Data Infrastructure 100%
  • Prevention Program 100%
  • Biostatistics 100%
  • Alzheimer's Disease 100%
  • Data Management 66%

• Administrative Core

  Luchsinger, J. (PI)

  9/1/23 → 8/31/24

  Projet

  • Administrative Structure 100%
  • Diabetes Prevention 100%
  • Diseases 80%
  • Alzheimer's Disease 66%
  • Education Program 40%

• ECM remodeling and crosstalk with cell fate in zebrafish ligament regeneration

  Mo, J. J. (PI)

  9/1/23 → 8/31/24

  Projet

  • Legumain 100%
  • Cell Fate 100%
  • Zebra Fish 100%
  • Macrophage 55%
  • Cysteine Protease 11%

• Administrative Core

  Califano, A. A. (PI)

  9/1/23 → 8/31/24

  Projet

  • Pilot Project 100%
  • Steering Committee 100%
  • Administrative Structure 100%
  • Progress Report 50%
  • Metrics 50%

• Single-Cell, Spatial and Functional Dissection of Cancer Cell States, Co-Evolving Ecosystems, and Vulnerabilities During Tumor Progression and Metastasis

  Izar, B. (PI)

  9/1/23 → 8/31/24

  Projet

  • Cancer Cell 100%
  • Tumor Progression 100%
  • Drug Resistance 66%
  • Immunity 66%
  • Human Study 33%

• Drug Mechanism of Action-based targeting of tumor subpopulations

  Califano, A. A. (PI)

  9/1/23 → 8/31/24

  Projet

  • Immune Checkpoints 100%
  • Small Molecule 100%
  • Oncogene 100%
  • Drug Mechanism 100%
  • Mouse Model 100%

• Outreach Core

  Murray, D. D. (PI)

  9/1/23 → 8/31/24

  Projet

  • Outreach 100%
  • Therapy 100%
  • Systems Biology 36%
  • Secondary Schools 36%
  • Scientists 27%

• Advanced Single Cell Technology Innovation Core

  Sims, P. P. A. (PI)

  9/1/23 → 8/31/24

  Projet

  • RNA Sequencing 100%
  • Malignant Neoplasm 100%
  • RNA 100%
  • Analytic Method 50%
  • Neoplasm 50%

• Structure-informed dissection of cancer-specific intracellular and paracrine networks

  Honig, B. H. (PI)

  9/1/23 → 8/31/24

  Projet

  • Receptor 100%
  • Malignant Neoplasm 100%
  • Signal Transduction 100%
  • Neoplasm 66%
  • Phosphoproteomics 66%

• DDRIG: Intimate Crises: The history of notions of sexuality and gender in the 19th and 20th century

  Sbitan, J. (CoPI) & Elshakry, M. (PI)

  National Science Foundation

  9/1/23 → 8/31/24

  Projet

  • Twentieth Century 100%
  • Nineteenth Century 100%
  • Social Exclusion 100%
  • Theses 66%
  • Public Health 50%

• BRAIN CONNECTS: The center for Large-scale Imaging of Neural Circuits (LINC)

  Yendiki, A. A. (PI), Hillman, E. M. C. (CoPI) & Haber, S. (CoPI)

  9/1/23 → 6/30/24

  Projet

  • Neural Circuit 100%
  • Axon 100%
  • Prefrontal Cortex 50%
  • Tourette Syndrome 25%
  • Magnetic Resonance Imaging 25%

• Project 3: A Transdisciplinary Approach to Increasing Phytonutrients in New Mexican Diets: A Kitchen-to-Lab-to-Table Model

  Greenlee, H. A. (PI)

  9/1/23 → 8/31/24

  Projet

  • Phytonutrients 100%
  • Chlorophyll 100%
  • Carotenoid 100%
  • Diet Quality 75%
  • Tocopherol 50%

• Uncovering novel mechanisms and potential therapeutic targets for IgA vasculitis through GWAS and systems-level analysis of regulatory networks.

  Liu, L. L. (PI)

  8/24/23 → 5/31/24

  Projet

  • IgA Vasculitis 100%
  • Genome Wide Association Study 100%
  • Regulatory Network 100%
  • Genetics 100%
  • Immunoglobulin A 100%

• Health Disparities in Hospice in Nursing Homes

  Stone, P. W. (PI), Dick, A. W. (CoPI) & Dhingra, L. (CoPI)

  8/23/23 → 6/30/24

  Projet

  • Nursing Home 100%
  • Health Disparity 100%
  • Hospice Care 40%
  • Terminal Care 20%
  • End of Life Care 20%

• Elucidating the Consequences of Chromosome 3 Arm Aneuploidies in Squamous Cell Carcinoma

  Taylor, A. A. M. (PI)

  8/21/23 → 7/31/24

  Projet

  • Aneuploidy 100%
  • Chromosome 3 100%
  • Chromosome Arm 50%
  • Chromosome 3q 50%
  • Carcinogenesis 33%

• Architecture, dynamics and regulation of erythrocyte ankyrin-1 complexes

  Clarke, O. O. B. (PI)

  8/20/23 → 7/31/24

  Projet

  • Dynamics 100%
  • Ankyrin 100%
  • Band 3 30%
  • Membrane Protein 30%
  • Transmembrane Protein 30%

• Development and application of a quantitive model for HIV-1 transcriptional activation driven by TAR RNA conformational dynamics

  Al-hashimi, H. H. M. (PI), Herschlag, D. D. (CoPI) & Goff, S. S. P. (CoPI)

  8/17/23 → 7/31/24

  Projet

  • Dynamics 100%
  • Human Immunodeficiency Virus 1 100%
  • Transcription Initiation 100%
  • RNA 100%
  • Transactivation 100%

• NY Community-Hospital-Academic Maternal Health Equity Partnerships (NY-CHAMP)

  Reddy, U. U. (PI), Rodriguez, E. E. (CoPI), Li, G. G. (CoPI), Taylor, J. J. Y. (CoPI), Hall, K. K. S. (CoPI), Osborne, L. L. M. (CoPI), Dorval-moller, M. M. (CoPI), Safford, M. M. M. (CoPI), Brown, S. S. (CoPI) & St. Clair, V. V. (CoPI)

  8/17/23 → 7/31/24

  Projet

  • Maternal Welfare 100%
  • Health Disparity 12%
  • Patient Care 12%
  • Health Care Cost 12%
  • Cognitive Behavioral Therapy 12%

• Non-APOL1 genetic factors and kidney transplant outcomes

  Kiryluk, K. K. (PI)

  8/15/23 → 5/31/24

  Projet

  • Heredity 100%
  • Kidney Graft 100%
  • Kidney Transplantation 100%
  • Genetics 100%
  • Genetic Determinism 100%

• Investigating the role of long-term latent herpes simplex virus infection on APOE4-associated Alzheimer's disease pathogenesis

  Nuriel, T. T. (PI) & Cliffe, A. A. R. (CoPI)

  8/15/23 → 4/30/24

  Projet

  • Virus Infection 100%
  • Human Alphaherpesvirus 1 100%
  • Herpes Simplex Virus 100%
  • Alzheimer's Disease 100%
  • Infection 83%

• Genetics and neurobiology of aggression of Betta splendens

  Shih, P. Y. P. (PI)

  8/15/23 → 7/31/24

  Projet

  • Social Behavior 100%
  • Nervous System 100%
  • Neuroscience 100%
  • Genetics 100%
  • Individual Differences 50%

• Impact of Environmental Exposures on Lung Immunity over Age

  Ural, B. B. (PI)

  8/15/23 → 4/30/24

  Projet

  • Environmental Exposure 100%
  • Macrophage 100%
  • Lung 100%
  • Diseases 100%
  • Lymph Node 71%

• Molecular Mechanisms of MDS pathogenesis with aging

  Kousteni, S. S. (PI)

  8/15/23 → 4/30/24

  Projet

  • Nucleoporin 100%
  • Stem Cell 37%
  • Hematopoiesis 12%
  • NUP98 12%
  • Molecular Genetics 12%

• Identification of smooth muscle cell genes causal in atherosclerotic plaque stability and cardiovascular disease risk

  Reilly, M. M. P. (PI) & Saleheen, D. D. (CoPI)

  8/10/23 → 6/30/24

  Projet

  • Mouse Model 100%
  • Single Nucleotide Polymorphism 66%
  • Pleiotropy 66%
  • RNA 66%
  • Genetics 33%

• Decoding the Interferome by Mapping Genetic Interactions in Human Tissue

  Gaudet, R. R. G. (PI)

  8/10/23 → 7/31/24

  Projet

  • Interferon-Stimulated Gene 100%
  • Human Tissue 100%
  • Gene Interaction 100%
  • Immunocompetent Cell 50%
  • Interferon Type I 25%

• Role of long non-coding RNAs in exosome biogenesis

  Momen Heravi, F. F. (PI)

  8/10/23 → 7/31/24

  Projet

  • Biogenesis 100%
  • Long Non-Coding RNA 100%
  • Exosome 100%
  • Long Noncoding RNA 66%
  • Cell Communication 33%

• Insulin regulation of hepatic transport

  Haeusler, R. R. A. (PI)

  8/9/23 → 5/31/24

  Projet

  • Bile Acid 100%
  • Bile 25%
  • Hepatocyte 25%
  • Insulin Resistance 12%
  • Public Health 12%

• Resilient Emotion Regulation Development in a South African Birth Cohort

  Tottenham, N. N. (PI), Tomlinson, M. M. (CoPI) & Seedat, S. S. (CoPI)

  8/2/23 → 6/30/24

  Projet

  • Protective Factor 100%
  • World Population 100%
  • Structural Health 100%
  • shape context 100%
  • Neural Correlate 100%

• SEARCH: SMS Electronic Adolescent Reminders for Completion of HPV vaccination- Uganda

  Stockwell, M. S. (PI) & Kitaka, S. B. (CoPI)

  8/1/23 → 7/31/24

  Projet

• 2/4-The INTEGRATE Study: Evaluating INTEGRATEd care to Improve Biopschosocial Outcomes of Early Liver Transplantation for Alcohol-Associated Liver Disease

  Verna, E. E. C. (PI)

  8/1/23 → 7/31/24

  Projet

• Engineered Hydrogel Elucidates the Contribution of ECM Stiffness to Barrett's Esophagus Pathogenesis

  Cruz Acuña, R. R. (PI)

  8/1/23 → 4/30/24

  Projet

  • Esophagus 100%
  • Rigidity 100%
  • Barrett Esophagus 100%
  • Metaplasia 20%
  • Organoid 20%

• Programmable encapsulation systems to improve delivery of therapeutic bacteria

  Danino, T. T. (PI), Leong, K. K. W. (CoPI) & Arpaia, N. N. (CoPI)

  8/1/23 → 7/31/24

  Projet

  • Neoplasm 100%
  • Probiotic 100%
  • Escherichia coli 100%
  • Triple Negative Breast Cancer 50%
  • Clinical Trial 50%

• Clearance of Dead Hepatocytes by Liver Macrophages in NASH

  Shi, H. H. (PI)

  8/1/23 → 7/31/24

  Projet

  • Macrophage 100%
  • Nonalcoholic Fatty Liver 100%
  • Hepatocyte 100%
  • Steatohepatitis 100%
  • Efferocytosis 22%

• Broad spectrum inhibitors of paramyxovirus envelope proteins

  Moscona, A. A. (PI)

  8/1/23 → 7/31/24

  Projet

  • Envelope Protein 100%
  • Paramyxoviridae 100%
  • Peptides 100%
  • Antivirus Agent 75%
  • Lipopeptide 75%

• Impact of biofeedback and task-specific training with a robotic hand orthosis on voluntary muscle modulation for rehabilitation post-stroke

  Chen, A. A. (PI)

  8/1/23 → 7/31/24

  Projet

  • Orthosis 100%
  • Biofeedback 100%
  • Stroke Rehabilitation 100%
  • robotic hand 100%
  • Electromyography 100%

• Collaborative Research: RAPID: A novel magnetometer network to capture the ongoing inflationary episode at Askja volcano, Iceland

  Lev, E. (CoPI) & Bacon, C. A. (PI)

  8/1/23 → 7/31/24

  Projet

  • Iceland 100%
  • Magma 100%
  • Magnetic Measurement 66%
  • United States 66%
  • GNSS 66%

• 3D Culture Models of Partial-EMT and Its Regulation in Oral Cavity Squamous Cell Carcinoma

  Parikh, A. A. S. (PI)

  8/1/23 → 7/31/24

  Projet

  • Oral Cavity 100%
  • Epithelial Mesenchymal Transition 100%
  • Squamous Cell Carcinoma 100%
  • TGFBI 100%
  • Growth Factor 77%

• Genetic and neuroanatomical basis of neuropsychiatric symptoms in Alzheimer's disease in populations of diverse ancestry

  Reitz, C. C. (PI), Huey, E. E. D. (CoPI) & Beecham, G. G. W. (CoPI)

  8/1/23 → 7/31/24

  Projet

  • Genetics 100%
  • Genomics 50%
  • Genetic Architecture 25%
  • FUS 25%
  • Genetic Risk 25%

• Impact of nucleotide metabolism on bacterial clearance

  Riquelme Colet, S. S. A. (PI)

  8/1/23 → 7/31/24

  Projet

  • Dihydroorotate Dehydrogenase 100%
  • Bacterial Clearance 100%
  • Nucleotide Metabolism 100%
  • Airway 100%
  • Infectious Agent 80%

• Cell-type-specific control of information flow between brain regions

  Zador, A. A. M. (PI)

  8/1/23 → 7/31/24

  Projet

  • In Vivo 100%
  • In Vitro 100%
  • Decision-Making 50%
  • Auditory Cortex 50%
  • Calcium Imaging 50%

• Dissecting the synaptic and circuit mechanisms underlying olfactory-driven social behavior

  Rodriguez, E. E. J. (PI)

  8/1/23 → 7/31/24

  Projet

  • Spectrum Disorder 100%
  • Social Behavior 100%
  • Behavior (Neuroscience) 100%

• Transcriptional regulation of urothelial differentiation and cell type specification during homeostasis and regeneration

  Mendelsohn, C. C. L. (PI)

  8/1/23 → 7/31/24

  Projet

  • Homeostasis 100%
  • Urology 100%
  • Urinary Tract Infection 100%
  • Regeneration 100%
  • Lower Urinary Tract Symptom 50%