DNA Polymerase delta synthesizes both strands during break-induced replication

  • Lorraine Symington (Contributor)
  • Roberto A Donnianni (Contributor)
  • Zhi-Xiong Zhou (Contributor)
  • Scott Lujan (Contributor)
  • Amr Al-Zain (Contributor)
  • Valerie Garcia (Contributor)
  • Thomas Kunkel (Contributor)
  • Adam Burkholder (Contributor)
  • Eleanor Glancy (Contributor)

Dataset

Description

In this study, the efficiency of break-induced replication was measure by physical assays (PCR or Southern blot hybridization of genomic DNA) in wild type (WT) and cells with mutations in each of the replicative DNA polymerases, or in cells with conditional depletion of the replicative DNA polymerases. Full details of data collection and analysis are presented in the accompanying paper.
Date made availableJul 11 2019
PublisherColumbia University

Cite this