Projects per year
Project Details
Description
PROJECT SUMMARY In this effort, we will analyze clinically-annotated tumor samples from 50 GBM patients at initial diagnosis and at time of recurrence (50 ?pairs?). We will perform single cell transcriptomic analyses at baseline and at recurrence, integrating cellular, molecular and phenotypic measurements with detailed clinical annotation, and histological and radiographic measurements to resolve the critical features that drive tumor evolution and disease progression. We will achieve this through a consortium of NCI Cancer Centers, and this will enable us to optimize statistical robustness and capture the extensive heterogeneity of the disease.
Status | Finished |
---|---|
Effective start/end date | 1/1/90 → 6/30/22 |
Funding
- National Cancer Institute: US$3,703,055.00
- National Cancer Institute: US$1,841,557.00
- National Cancer Institute: US$305,652.00
ASJC Scopus Subject Areas
- Cancer Research
- Oncology
- Medicine(all)
- Health Professions(all)
- Computer Science Applications
- Health Informatics
- Statistics and Probability
- Cell Biology
- Genetics
- Molecular Biology
- Pathology and Forensic Medicine
- Public Health, Environmental and Occupational Health
- Pediatrics, Perinatology, and Child Health
- Immunology
- Virology
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Projects
- 19 Finished
-
Leadership, Planning, and Evaluation
Rustgi, A. K. (PI) & Rustgi, A. A. K. (PI)
7/1/20 → 6/30/22
Project: Research project
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Cancer Research Career Enhancement
Chung, W. K. (PI) & Chung, W. W. K. (PI)
7/1/20 → 6/30/22
Project: Research project
-
Genetically Modified Mouse Models
Costantini, F. D. (PI) & Que, J. J. (PI)
7/1/20 → 6/30/22
Project: Research project