Project Details
Description
The tau protein is important for maintaining neuronal health in the central nervous system. When tau is misfolded, it accumulates and becomes a key pathological feature in Alzheimer's disease and frontotemporal dementia. Dr. Jessica Wu and her colleagues have determined that misfolded tau is taken up in neurons. This project aims to document how misfolded tau is released from neurons and is then subsequently taken up by surrounding neurons to spread pathology in diseases.
Status | Finished |
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Effective start/end date | 7/1/12 → 6/30/14 |
Funding
- BrightFocus Foundation: US$100,000.00
ASJC Scopus Subject Areas
- Clinical Neurology
- Neurology
- Medicine(all)
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