PEPTIDE RECOGNITION BY CLASS I MHC PROTEINS

Project: Research project

Project Details

Description

Thisprojectisverysimilartothepreviousoneinthatweare trying to calculate relative binding energies of different peptides to a single protein whose structure is known. Our goal in this project is to elucidate the principles of specific peptide recognition, a problem of far-reaching implications in biology. We are trying now to identify those interactions that give rise to specificity by calculating the contributions of individual amino acids to the binding energy.
StatusFinished
Effective start/end date10/1/959/30/99

Funding

  • National Center for Research Resources: US$43,625.00

ASJC Scopus Subject Areas

  • Radiation
  • Statistics, Probability and Uncertainty
  • Biochemistry, Genetics and Molecular Biology(all)

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