Role of SUMOylation in Alzheimer's Disease

After proteins are mADe inside cells, they are often modified by the attachment of large organic molecules. This process is an important way for the cell to control a protein's function and location. One type of modification is called SUMOylation (SUMO is an acronym for small ubiquitin-like modifiers). SUMOylation of proteins serves a number of important cellular functions, and there is evidence that it plays a role in some cellular models of learning and memory.