Project Details
Description
Narrative
Barrett’s esophagus is a strong risk factor for esophageal adenocarcinoma which has become the most rapidly
increasing cancer in the United States. The mechanism promoting Barrett’s metaplasia, however, remains
unknown. This proposal will determine how the Wnt/SOX4 axis drives Barrett’s pathogenesis, meanwhile testing
drugs that block the axis for potential therapeutic gains against the disease.
| Status | Finished |
|---|---|
| Effective start/end date | 5/20/19 → 2/28/23 |
Funding
- National Institute of Diabetes and Digestive and Kidney Diseases: US$436,739.00
- National Institute of Diabetes and Digestive and Kidney Diseases: US$387,698.00
ASJC Scopus Subject Areas
- Cancer Research
- Biotechnology
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