The role of inflammation in the association between diet and Alzheimer's disease

Relevance Promoting healthy aging and preventing late-onset Alzheimer’s disease (LOAD) is of increasing concern to an aging population. The proposed study will have the potential to advance the field and enhance our understanding on biological mechanisms between diet and multiple aspects of the diseases span, ranging from early structural changes in the brain, to the cognitive impairments, and ultimately to the clinical diagnosis of LOAD. Obtaining insight into the role of inflammation in the context of diet and LOAD will assist to prioritize public health efforts and provide a firm foundation for dietary recommendations on cognitive health and resilience.