Weight Loss, Gain, and Cycling, Dietary and Lifestyle Patterns and Risk of Pancreatic Cancer

Project Description Pancreatic cancer incidence is increasing and 50% of people die within 6 months of diagnosis. Few modifiable factors are known to lower pancreatic cancer incidence. Diet and obesity may be important, yet the effects of weight changes, or following dietary guidelines on pancreatic cancer are not known. Dr. Genkinger will examine whether 1) weight loss, gain and cycling and 2) adherence to dietary and lifestyle patterns affects pancreatic cancer risk. Merging data from over 12 cohorts, the team will study diet, body weight and pancreatic cancer in the Pooling Project of Prospective Studies of Diet and Cancer. By addressing these research questions, the results will provide the most complete evidence on these important factors, and advance knowledge about these factors for a highly fatal disease.