An International Laboratory for Systems and Computational Neuroscience

The International Brain Laboratory

Research output: Contribution to journalShort surveypeer-review

43 Citations (Scopus)

Abstract

The neural basis of decision-making has been elusive and involves the coordinated activity of multiple brain structures. This NeuroView, by the International Brain Laboratory (IBL), discusses their efforts to develop a standardized mouse decision-making behavior, to make coordinated measurements of neural activity across the mouse brain, and to use theory and analyses to uncover the neural computations that support decision-making. The neural basis of decision-making has been elusive and involves the coordinated activity of multiple brain structures. This NeuroView, by the International Brain Laboratory (IBL), discusses their efforts to develop a standardized mouse decision-making behavior, to make coordinated measurements of neural activity across the mouse brain, and to use theory and analyses to uncover the neural computations that support decision-making.

Original languageEnglish
Pages (from-to)1213-1218
Number of pages6
JournalNeuron
Volume96
Issue number6
DOIs
Publication statusPublished - Dec 20 2017

Bibliographical note

Publisher Copyright:
© 2017

Funding

Despite these challenges, collaborative efforts in neuroscience are emerging. Examples within academia include the BRAIN initiative, the IARPA MICRONS project, the HCP, the NSF NeuroNex projects, and the Human Brain Project ( Yuste and Bargmann, 2017 ). These efforts bring together larger teams of researchers to develop new technologies and drive forward our understanding of brain function. IBL is much smaller and it has a singular focus: mapping brain-wide activity at single-neuron resolution during a single behavioral task. The International Brain Laboratory is funded by the Wellcome Trust , the Simons Foundation , and the INCF . We thank David Tank and Carlos Brody for advice during the formation of our collaboration.

FundersFunder number
INCF
National Science Foundation
National Institute of Biomedical Imaging and BioengineeringR01EB022913
Simons Foundation
Wellcome Trust
Intelligence Advanced Research Projects Activity

    ASJC Scopus Subject Areas

    • General Neuroscience

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