Biologics in the Management of Rotator Cuff Surgery

Michael E. Angeline; Scott A. Rodeo

doi:10.1016/j.csm.2012.07.003

Biologics in the Management of Rotator Cuff Surgery

Michael E. Angeline, Scott A. Rodeo

Hospital for Special Surgery

Research output: Contribution to journal › Review article › peer-review

66 Citations (Scopus)

Abstract

Surgical repair of rotator cuff tears is a relatively common orthopedic procedure. Although the procedure is clinically successful, the repair site frequently has incomplete healing and gap formation, owing to a fibrovascular scar-mediated healing response at the tendon-bone interface. By augmenting the repair site with biological agents, the ultimate goal is to stimulate a regenerative healing pathway. Challenges remain, however, regarding the ideal factor(s), timing, and vehicle of delivery.

Original language	English
Pages (from-to)	645-663
Number of pages	19
Journal	Clinics in Sports Medicine
Volume	31
Issue number	4
DOIs	https://doi.org/10.1016/j.csm.2012.07.003
Publication status	Published - Oct 2012

ASJC Scopus Subject Areas

Orthopedics and Sports Medicine
Physical Therapy, Sports Therapy and Rehabilitation

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10.1016/j.csm.2012.07.003

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abstract = "Surgical repair of rotator cuff tears is a relatively common orthopedic procedure. Although the procedure is clinically successful, the repair site frequently has incomplete healing and gap formation, owing to a fibrovascular scar-mediated healing response at the tendon-bone interface. By augmenting the repair site with biological agents, the ultimate goal is to stimulate a regenerative healing pathway. Challenges remain, however, regarding the ideal factor(s), timing, and vehicle of delivery.",

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AB - Surgical repair of rotator cuff tears is a relatively common orthopedic procedure. Although the procedure is clinically successful, the repair site frequently has incomplete healing and gap formation, owing to a fibrovascular scar-mediated healing response at the tendon-bone interface. By augmenting the repair site with biological agents, the ultimate goal is to stimulate a regenerative healing pathway. Challenges remain, however, regarding the ideal factor(s), timing, and vehicle of delivery.

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Biologics in the Management of Rotator Cuff Surgery

Abstract

ASJC Scopus Subject Areas

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