Chloroquine-resistant falciparum malaria in northern Malawi

M. S. Wolfe; J. G. Breman; B. Ainsworth; A. Teklehaimanot; L. C. Patchen

doi:10.4269/ajtmh.1985.34.847

Chloroquine-resistant falciparum malaria in northern Malawi

M. S. Wolfe, J. G. Breman, B. Ainsworth, A. Teklehaimanot, L. C. Patchen

The Earth Institute

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

An American Peace Corps volunteer contracted chloroquine-resistant Plasmodium falciparum malaria while serving in Malawi and taking regular chloroquine prophylaxis. Resistance was confirmed by in vitro testing of his parasites for chloroquine and pyrimethamine. The possibility of Fansidar®-resistant falciparum malaria was also suggested in this case. American expatriates residing in or traveling to Malawi are advised to either take both chloroquine and Fansidar®, or alternatively amodiaquine or doxycycline alone. Any breakthrough of slide-proven falciparum malaria in these individuals should be seriously suspected to be chloroquine- and Fansidar®-resistant malaria, and should be treated with quinine and tetracycline.

Original language	English
Pages (from-to)	847-849
Number of pages	3
Journal	American Journal of Tropical Medicine and Hygiene
Volume	34
Issue number	5
DOIs	https://doi.org/10.4269/ajtmh.1985.34.847
Publication status	Published - 1985

ASJC Scopus Subject Areas

Parasitology
Infectious Diseases
Virology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.4269/ajtmh.1985.34.847

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title = "Chloroquine-resistant falciparum malaria in northern Malawi",

abstract = "An American Peace Corps volunteer contracted chloroquine-resistant Plasmodium falciparum malaria while serving in Malawi and taking regular chloroquine prophylaxis. Resistance was confirmed by in vitro testing of his parasites for chloroquine and pyrimethamine. The possibility of Fansidar{\textregistered}-resistant falciparum malaria was also suggested in this case. American expatriates residing in or traveling to Malawi are advised to either take both chloroquine and Fansidar{\textregistered}, or alternatively amodiaquine or doxycycline alone. Any breakthrough of slide-proven falciparum malaria in these individuals should be seriously suspected to be chloroquine- and Fansidar{\textregistered}-resistant malaria, and should be treated with quinine and tetracycline.",

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T1 - Chloroquine-resistant falciparum malaria in northern Malawi

AU - Wolfe, M. S.

AU - Breman, J. G.

AU - Ainsworth, B.

AU - Teklehaimanot, A.

AU - Patchen, L. C.

PY - 1985

Y1 - 1985

N2 - An American Peace Corps volunteer contracted chloroquine-resistant Plasmodium falciparum malaria while serving in Malawi and taking regular chloroquine prophylaxis. Resistance was confirmed by in vitro testing of his parasites for chloroquine and pyrimethamine. The possibility of Fansidar®-resistant falciparum malaria was also suggested in this case. American expatriates residing in or traveling to Malawi are advised to either take both chloroquine and Fansidar®, or alternatively amodiaquine or doxycycline alone. Any breakthrough of slide-proven falciparum malaria in these individuals should be seriously suspected to be chloroquine- and Fansidar®-resistant malaria, and should be treated with quinine and tetracycline.

AB - An American Peace Corps volunteer contracted chloroquine-resistant Plasmodium falciparum malaria while serving in Malawi and taking regular chloroquine prophylaxis. Resistance was confirmed by in vitro testing of his parasites for chloroquine and pyrimethamine. The possibility of Fansidar®-resistant falciparum malaria was also suggested in this case. American expatriates residing in or traveling to Malawi are advised to either take both chloroquine and Fansidar®, or alternatively amodiaquine or doxycycline alone. Any breakthrough of slide-proven falciparum malaria in these individuals should be seriously suspected to be chloroquine- and Fansidar®-resistant malaria, and should be treated with quinine and tetracycline.

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Chloroquine-resistant falciparum malaria in northern Malawi

Abstract

ASJC Scopus Subject Areas

UN SDGs

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