Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure

Pablo F. Castro; Paul Mc-Nab; Juan Carlos Quintana; Alex Bittner; Douglas Greig; Ismael Vergara; José Luis Vukasovic; Ramón Corbalan; Miguel Copaja; Guillermo Díaz-Araya; Mario Chiong; Rodrigo Troncoso; Hernán Alcaino; Sergio Lavandero

doi:10.1016/j.amjcard.2005.03.057

Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure

Pablo F. Castro, Paul Mc-Nab, Juan Carlos Quintana, Alex Bittner, Douglas Greig, Ismael Vergara, José Luis Vukasovic, Ramón Corbalan, Miguel Copaja, Guillermo Díaz-Araya, Mario Chiong, Rodrigo Troncoso, Hernán Alcaino, Sergio Lavandero

Universidad de Chile

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Radionuclide isotopic ventriculography with phase analysis was performed in 30 patients with stable heart failure (HF), determining left ventricular (LV) and interventricular contraction synchrony at baseline and after 6 months of treatment with maximal tolerated doses of carvedilol. Patients with HF had significant ventricular dyssynchrony compared with a normal population. The 50th percentile of patients with the greatest dyssynchrony at baseline showed significant improvement in ventricular synchrony after receiving carvedilol, and this was correlated positively with a reduction in end-diastolic LV volumes.

Original language	English
Pages (from-to)	267-269
Number of pages	3
Journal	American Journal of Cardiology
Volume	96
Issue number	2
DOIs	https://doi.org/10.1016/j.amjcard.2005.03.057
Publication status	Published - Jul 15 2005

Bibliographical note

Funding Information:
Dr. Castro was supported in part by FONDECYT (Santiago, Chile) grant 1010992 and Dr. Lavandero by FONDAP (Santiago, Chile) grant 1501006.

Funding

Dr. Castro was supported in part by FONDECYT (Santiago, Chile) grant 1010992 and Dr. Lavandero by FONDAP (Santiago, Chile) grant 1501006.

Funders	Funder number
Fondo Nacional de Desarrollo Científico y Tecnológico	1010992
Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias	1501006

ASJC Scopus Subject Areas

Cardiology and Cardiovascular Medicine

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10.1016/j.amjcard.2005.03.057

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Castro, P. F., Mc-Nab, P., Quintana, J. C., Bittner, A., Greig, D., Vergara, I., Vukasovic, J. L., Corbalan, R., Copaja, M., Díaz-Araya, G., Chiong, M., Troncoso, R., Alcaino, H., & Lavandero, S. (2005). Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure. American Journal of Cardiology, 96(2), 267-269. https://doi.org/10.1016/j.amjcard.2005.03.057

Castro, PF, Mc-Nab, P, Quintana, JC, Bittner, A, Greig, D, Vergara, I, Vukasovic, JL, Corbalan, R, Copaja, M, Díaz-Araya, G, Chiong, M, Troncoso, R, Alcaino, H & Lavandero, S 2005, 'Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure', American Journal of Cardiology, vol. 96, no. 2, pp. 267-269. https://doi.org/10.1016/j.amjcard.2005.03.057

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title = "Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure",

abstract = "Radionuclide isotopic ventriculography with phase analysis was performed in 30 patients with stable heart failure (HF), determining left ventricular (LV) and interventricular contraction synchrony at baseline and after 6 months of treatment with maximal tolerated doses of carvedilol. Patients with HF had significant ventricular dyssynchrony compared with a normal population. The 50th percentile of patients with the greatest dyssynchrony at baseline showed significant improvement in ventricular synchrony after receiving carvedilol, and this was correlated positively with a reduction in end-diastolic LV volumes.",

author = "Castro, {Pablo F.} and Paul Mc-Nab and Quintana, {Juan Carlos} and Alex Bittner and Douglas Greig and Ismael Vergara and Vukasovic, {Jos{\'e} Luis} and Ram{\'o}n Corbalan and Miguel Copaja and Guillermo D{\'i}az-Araya and Mario Chiong and Rodrigo Troncoso and Hern{\'a}n Alcaino and Sergio Lavandero",

note = "Funding Information: Dr. Castro was supported in part by FONDECYT (Santiago, Chile) grant 1010992 and Dr. Lavandero by FONDAP (Santiago, Chile) grant 1501006. ",

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doi = "10.1016/j.amjcard.2005.03.057",

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AU - Greig, Douglas

AU - Vergara, Ismael

AU - Vukasovic, José Luis

AU - Corbalan, Ramón

AU - Copaja, Miguel

AU - Díaz-Araya, Guillermo

AU - Chiong, Mario

AU - Troncoso, Rodrigo

AU - Alcaino, Hernán

AU - Lavandero, Sergio

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Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure

Abstract

Bibliographical note

Funding

ASJC Scopus Subject Areas

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