Evidence for sensory prediction deficits in schizophrenia

Sukhwinder S. Shergill, Gabrielle Samson, Paul M. Bays, Chris D. Frith, Daniel M. Wolpert

Research output: Contribution to journalArticlepeer-review

332 Citations (Scopus)

Abstract

Objective: Patients with schizophrenia experiencing delusions and hallucinations can misattribute their own actions to an external source. The authors test the hypothesis that patients with schizophrenia have defects in their ability to predict the sensory consequences of their actions. Method: The authors measured sensory attenuation of self-produced stimuli by patients with schizophrenia and by healthy subjects. Results: Patients with schizophrenia demonstrated significantly less sensory attenuation than healthy subjects. Conclusions: Patients with a diagnosis of schizophrenia have a dysfunction in their predictive mechanisms.

Original languageEnglish
Pages (from-to)2384-2386
Number of pages3
JournalAmerican Journal of Psychiatry
Volume162
Issue number12
DOIs
Publication statusPublished - Dec 2005

ASJC Scopus Subject Areas

  • Psychiatry and Mental health

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