Image based weighted center of proximity versus directly measured knee contact location during simulated gait

Hongsheng Wang, Tony Chen, Matthew F. Koff, Ian D. Hutchinson, Susannah Gilbert, Dan Choi, Russell F. Warren, Scott A. Rodeo, Suzanne A. Maher

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

To understand the mechanical consequences of knee injury requires a detailed analysis of the effect of that injury on joint contact mechanics during activities of daily living. Three-dimensional (3D) knee joint geometric models have been combined with knee joint kinematics to dynamically estimate the location of joint contact during physiological activities-using a weighted center of proximity (WCoP) method. However, the relationship between the estimated WCoP and the actual location of contact has not been defined. The objective of this study was to assess the relationship between knee joint contact location as estimated using the image-based WCoP method, and a directly measured weighted center of contact (WCoC) method during simulated walking. To achieve this goal, we created knee specific models of six human cadaveric knees from magnetic resonance imaging. All knees were then subjected to physiological loads on a knee simulator intended to mimic gait. Knee joint motion was captured using a motion capture system. Knee joint contact stresses were synchronously recorded using a thin electronic sensor throughout gait, and used to compute WCoC for the medial and lateral plateaus of each knee. WCoP was calculated by combining knee kinematics with the MRI-based knee specific model. Both metrics were compared throughout gait using linear regression. The anteroposterior (AP) location of WCoP was significantly correlated with that of WCoC on both tibial plateaus in all specimens (p<0.01, 95% confidence interval of Pearson's coefficient r>0), but the correlation was not significant in the mediolateral (ML) direction for 4/6 knees (p>0.05). Our study demonstrates that while the location of joint contact obtained from 3D knee joint contact model, using the WCoP method, is significantly correlated with the location of actual contact stresses in the AP direction, that relationship is less certain in the ML direction.

Original languageEnglish
Pages (from-to)2483-2489
Number of pages7
JournalJournal of Biomechanics
Volume47
Issue number10
DOIs
Publication statusPublished - Jul 18 2014

Bibliographical note

Funding Information:
Research reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award Number AR057343 and KL2 TR000458. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Support was also provided by the American Orthopaedic Society for Sports Medicine (AOSSM) and the Russell Warren Chair in Tissue Engineering.

Funding

Research reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award Number AR057343 and KL2 TR000458. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Support was also provided by the American Orthopaedic Society for Sports Medicine (AOSSM) and the Russell Warren Chair in Tissue Engineering.

FundersFunder number
National Institutes of HealthAR057343
National Institute of Arthritis and Musculoskeletal and Skin Diseases
National Center for Advancing Translational SciencesKL2TR000458

    ASJC Scopus Subject Areas

    • Biophysics
    • Biomedical Engineering
    • Orthopedics and Sports Medicine
    • Rehabilitation

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