Muscle Injuries in Athletes: Enhancing Recovery Through Scientific Understanding and Novel Therapies

Context: Muscle injuries are extremely common in athletes and often produce pain, dysfunction, and the inability toreturn to practice or competition. Appropriate diagnosis and management can optimize recovery and minimize time toreturn to play.Evidence Acquisition: Contemporary papers, both basic science and clinical medicine, that investigate muscle healingwere reviewed. A Medline/PubMed search inclusive of years 1948 to 2012 was performed.Results: Diagnosis can usually be made according to history and physical examination for most injuries. Although data arelimited, initial conservative management emphasizing the RICE principles and immobilization of the extremity for severaldays for higher grade injuries are typically all that is required. Injection of corticosteroids may clinically enhance functionafter an acute muscle strain. Additional adjunctive treatments (nonsteroidal anti-inflammatory drugs, platelet-rich plasma,and others) to enhance muscle healing and limit scar formation show promise but need additional data to better define theirroles.Conclusion: Conservative treatment recommendations will typically lead to successful outcomes after a muscle injury.There is limited evidence to support most adjunctive treatments.