Abstract
Orthobiologics are a group of biological materials and substrates that promote bone, ligament, muscle, and tendon healing. These substances include bone autograft, bone allograft, demineralized bone matrix, bone graft substitutes, bone marrow aspirate concentrate, platelet-rich plasma, bone morphogenetic proteins, platelet-derived growth factor, parathyroid hormone, and vitamin D and calcium. Properties of orthobiologics in bone healing include osteoconduction, osteoinduction, and osteogenesis. This article discusses the important properties of orthobiologics in bone healing, many of the orthobiologics currently available for bone healing, the related literature, their current clinical uses in sports medicine, and systemic factors that inhibit bone healing.
| Original language | English |
|---|---|
| Pages (from-to) | 79-95 |
| Number of pages | 17 |
| Journal | Clinics in Sports Medicine |
| Volume | 38 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 2019 |
Bibliographical note
Publisher Copyright:© 2018 Elsevier Inc.
ASJC Scopus Subject Areas
- Orthopedics and Sports Medicine
- Physical Therapy, Sports Therapy and Rehabilitation