Sodium lactate response and familial risk for panic disorder

Anat H. Reschke, Salvatore Mannuzza, Tim F. Chapman, Joshua D. Lipsitz, Michael R. Liebowitz, Jack M. Gorman, Donald F. Klein, Abby J. Fyer

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Objective: The authors used the family study method to test the hypothesis that sodium lactate response defines two subtypes of panic disorder. Method: Rates of panic disorder in 142 first-degree relatives of patients who responded to sodium lactate, 88 first-degree relatives of patients who did not respond to sodium lactate, and 231 first-degree relatives of never mentally ill subjects were compared. Results: No difference in familial transmission of panic disorder was found between the two patient groups. Conclusions: The findings do not support the notion that panic disorder subtypes are associated with lactate sensitivity.

Original languageEnglish
Pages (from-to)277-279
Number of pages3
JournalAmerican Journal of Psychiatry
Volume152
Issue number2
DOIs
Publication statusPublished - Feb 1995

Funding

FundersFunder number
National Institute of Mental HealthR01MH023864

    ASJC Scopus Subject Areas

    • Psychiatry and Mental health

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