Specificity of lactate infusions in social phobia versus panic disorders

M. R. Liebowitz; A. J. Fyer; J. M. Gorman; D. Dillon; S. Davies; J. M. Stein; B. S. Cohen; D. F. Klein

doi:10.1176/ajp.142.8.947

Specificity of lactate infusions in social phobia versus panic disorders

M. R. Liebowitz, A. J. Fyer, J. M. Gorman, D. Dillon, S. Davies, J. M. Stein, B. S. Cohen, D. F. Klein

Vagelos College of Physicians and Surgeons

Research output: Contribution to journal › Article › peer-review

112 Citations (Scopus)

Abstract

Lactate infusions produced panic attacks in one of 15 patients with social phobia, four of nine with agoraphobia, and 10 of 20 with panic disorder in a blind study. The proportion of patients with social phobia who panicked in response to lactate was significantly lower than that of patients with agoraphobia or panic disorder. These findings lend validity to the DSM-III classification of anxiety states. They also suggest that the pathophysiology of social phobia differs from that of disorders characterized by spontaneous panic attacks.

Original language	English
Pages (from-to)	947-950
Number of pages	4
Journal	American Journal of Psychiatry
Volume	142
Issue number	8
DOIs	https://doi.org/10.1176/ajp.142.8.947
Publication status	Published - 1985

ASJC Scopus Subject Areas

Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1176/ajp.142.8.947

Cite this

@article{b854eb1022104b9fa6865ae32e5a179f,

title = "Specificity of lactate infusions in social phobia versus panic disorders",

abstract = "Lactate infusions produced panic attacks in one of 15 patients with social phobia, four of nine with agoraphobia, and 10 of 20 with panic disorder in a blind study. The proportion of patients with social phobia who panicked in response to lactate was significantly lower than that of patients with agoraphobia or panic disorder. These findings lend validity to the DSM-III classification of anxiety states. They also suggest that the pathophysiology of social phobia differs from that of disorders characterized by spontaneous panic attacks.",

author = "Liebowitz, {M. R.} and Fyer, {A. J.} and Gorman, {J. M.} and D. Dillon and S. Davies and Stein, {J. M.} and Cohen, {B. S.} and Klein, {D. F.}",

year = "1985",

doi = "10.1176/ajp.142.8.947",

language = "English",

volume = "142",

pages = "947--950",

journal = "American Journal of Psychiatry",

issn = "0002-953X",

publisher = "American Psychiatric Association",

number = "8",

}

TY - JOUR

T1 - Specificity of lactate infusions in social phobia versus panic disorders

AU - Liebowitz, M. R.

AU - Fyer, A. J.

AU - Gorman, J. M.

AU - Dillon, D.

AU - Davies, S.

AU - Stein, J. M.

AU - Cohen, B. S.

AU - Klein, D. F.

PY - 1985

Y1 - 1985

N2 - Lactate infusions produced panic attacks in one of 15 patients with social phobia, four of nine with agoraphobia, and 10 of 20 with panic disorder in a blind study. The proportion of patients with social phobia who panicked in response to lactate was significantly lower than that of patients with agoraphobia or panic disorder. These findings lend validity to the DSM-III classification of anxiety states. They also suggest that the pathophysiology of social phobia differs from that of disorders characterized by spontaneous panic attacks.

AB - Lactate infusions produced panic attacks in one of 15 patients with social phobia, four of nine with agoraphobia, and 10 of 20 with panic disorder in a blind study. The proportion of patients with social phobia who panicked in response to lactate was significantly lower than that of patients with agoraphobia or panic disorder. These findings lend validity to the DSM-III classification of anxiety states. They also suggest that the pathophysiology of social phobia differs from that of disorders characterized by spontaneous panic attacks.

UR - http://www.scopus.com/inward/record.url?scp=0021926149&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021926149&partnerID=8YFLogxK

U2 - 10.1176/ajp.142.8.947

DO - 10.1176/ajp.142.8.947

M3 - Article

AN - SCOPUS:0021926149

SN - 0002-953X

VL - 142

SP - 947

EP - 950

JO - American Journal of Psychiatry

JF - American Journal of Psychiatry

IS - 8

ER -

Specificity of lactate infusions in social phobia versus panic disorders

Abstract

ASJC Scopus Subject Areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this