Technology for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva IPC-Think Tank (Part 2)

Walter Zingg; Benjamin J. Park; Julie Storr; Raheelah Ahmad; Carolyn Tarrant; Enrique Castro-Sanchez; Eli Perencevich; Andreas Widmer; Karl Heinz Krause; Claire Kilpatrick; Sara Tomczyk; Benedetta Allegranzi; Denise Cardo; Didier Pittet; Mohamed Abbas; Antoine Andremont; Mike Bell; Michael Borg; Yehuda Carmeli; John Conly; Philippe Eggimann; Petra Gastmeier; M. Lindsay Grayson; Stephan Harbarth; Marcela Hernandez; Loreen Herwaldt; Alison Holmes; John A. Jernigan; Amy Kolwaite; Elaine Larson; Sarah Masson-Roy; Shaheen Mehtar; Marc Mendelson; Ling Moi Lin; Andreea Moldovan; Dominique Monnet; Babacar Ndoye; Peter Nthumba; Folasade Ogunsola; Matthew Samore; Wing Hong Seto; Arjun Srinivasan; Evelina Tacconelli; Maha Talaat; Maria Virginia Villegas; Andreas Voss; Tim Walsh

doi:10.1186/s13756-019-0538-y

Technology for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva IPC-Think Tank (Part 2)

Walter Zingg, Benjamin J. Park, Julie Storr, Raheelah Ahmad, Carolyn Tarrant, Enrique Castro-Sanchez, Eli Perencevich, Andreas Widmer, Karl Heinz Krause, Claire Kilpatrick, Sara Tomczyk, Benedetta Allegranzi, Denise Cardo, Didier Pittet, Mohamed Abbas, Antoine Andremont, Mike Bell, Michael Borg, Yehuda Carmeli, John ConlyPhilippe Eggimann, Petra Gastmeier, M. Lindsay Grayson, Stephan Harbarth, Marcela Hernandez, Loreen Herwaldt, Alison Holmes, John A. Jernigan, Amy Kolwaite, Elaine Larson, Sarah Masson-Roy, Shaheen Mehtar, Marc Mendelson, Ling Moi Lin, Andreea Moldovan, Dominique Monnet, Babacar Ndoye, Peter Nthumba, Folasade Ogunsola, Matthew Samore, Wing Hong Seto, Arjun Srinivasan, Evelina Tacconelli, Maha Talaat, Maria Virginia Villegas, Andreas Voss, Tim Walsh

School of Nursing

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Background: The high burden of healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) is partially due to excessive antimicrobial use both in human and animal medicine worldwide. How can technology help to overcome challenges in infection prevention and control (IPC) and to prevent HAI and emerging AMR? Methods: In June 2017, 42 international experts convened in Geneva, Switzerland to discuss four potential domains of technology in IPC and AMR: 1) role and potential contribution of microbiome research; 2) whole genome sequencing; 3) effectiveness and benefit of antimicrobial environmental surfaces; and 4) future research in hand hygiene. Results: Research on the microbiome could expand understanding of antimicrobial use and also the role of probiotics or even faecal transplantation for therapeutic purposes. Whole genome sequencing will provide new insights in modes of transmission of infectious diseases. Although it is a powerful tool for public health epidemiology, some challenges with interpretation and costs still need to be addressed. The effectiveness and cost-effectiveness of antimicrobially coated or treated environmental high-touch surfaces requires further research before they can be recommended for routine use. Hand hygiene implementation can be advanced, where technological enhancement of surveillance, technique and compliance are coupled with reminders for healthcare professionals. Conclusions: The four domains of technological innovation contribute to the prevention of HAI and AMR at different levels. Microbiome research may offer innovative concepts for future prevention, whole genome sequencing could detect new modes of transmission and become an additional tool for effective public health epidemiology, antimicrobial surfaces might help to decrease the environment as source of transmission but continue to raise more questions than answers, and technological innovation may have a role in improving surveillance approaches and supporting best practice in hand hygiene.

Original language	English
Article number	83
Journal	Antimicrobial Resistance and Infection Control
Volume	8
Issue number	1
DOIs	https://doi.org/10.1186/s13756-019-0538-y
Publication status	Published - May 22 2019

Bibliographical note

Publisher Copyright:
© 2019 The Author(s).

Funding

The 2017 Geneva IPC-Think Tank was supported by the US Centers for Disease Prevention and Control, and the University of Geneva Hospitals, Switzerland.

Funders	Funder number
Centers for Disease Control and Prevention
Hôpitaux Universitaires de Genève

ASJC Scopus Subject Areas

Public Health, Environmental and Occupational Health
Microbiology (medical)
Infectious Diseases
Pharmacology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1186/s13756-019-0538-y

Cite this

Zingg, W., Park, B. J., Storr, J., Ahmad, R., Tarrant, C., Castro-Sanchez, E., Perencevich, E., Widmer, A., Krause, K. H., Kilpatrick, C., Tomczyk, S., Allegranzi, B., Cardo, D., Pittet, D., Abbas, M., Andremont, A., Bell, M., Borg, M., Carmeli, Y., ... Walsh, T. (2019). Technology for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva IPC-Think Tank (Part 2). Antimicrobial Resistance and Infection Control, 8(1), Article 83. https://doi.org/10.1186/s13756-019-0538-y

Zingg, W, Park, BJ, Storr, J, Ahmad, R, Tarrant, C, Castro-Sanchez, E, Perencevich, E, Widmer, A, Krause, KH, Kilpatrick, C, Tomczyk, S, Allegranzi, B, Cardo, D, Pittet, D, Abbas, M, Andremont, A, Bell, M, Borg, M, Carmeli, Y, Conly, J, Eggimann, P, Gastmeier, P, Grayson, ML, Harbarth, S, Hernandez, M, Herwaldt, L, Holmes, A, Jernigan, JA, Kolwaite, A, Larson, E, Masson-Roy, S, Mehtar, S, Mendelson, M, Lin, LM, Moldovan, A, Monnet, D, Ndoye, B, Nthumba, P, Ogunsola, F, Samore, M, Seto, WH, Srinivasan, A, Tacconelli, E, Talaat, M, Villegas, MV, Voss, A & Walsh, T 2019, 'Technology for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva IPC-Think Tank (Part 2)', Antimicrobial Resistance and Infection Control, vol. 8, no. 1, 83. https://doi.org/10.1186/s13756-019-0538-y

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title = "Technology for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva IPC-Think Tank (Part 2)",

abstract = "Background: The high burden of healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) is partially due to excessive antimicrobial use both in human and animal medicine worldwide. How can technology help to overcome challenges in infection prevention and control (IPC) and to prevent HAI and emerging AMR? Methods: In June 2017, 42 international experts convened in Geneva, Switzerland to discuss four potential domains of technology in IPC and AMR: 1) role and potential contribution of microbiome research; 2) whole genome sequencing; 3) effectiveness and benefit of antimicrobial environmental surfaces; and 4) future research in hand hygiene. Results: Research on the microbiome could expand understanding of antimicrobial use and also the role of probiotics or even faecal transplantation for therapeutic purposes. Whole genome sequencing will provide new insights in modes of transmission of infectious diseases. Although it is a powerful tool for public health epidemiology, some challenges with interpretation and costs still need to be addressed. The effectiveness and cost-effectiveness of antimicrobially coated or treated environmental high-touch surfaces requires further research before they can be recommended for routine use. Hand hygiene implementation can be advanced, where technological enhancement of surveillance, technique and compliance are coupled with reminders for healthcare professionals. Conclusions: The four domains of technological innovation contribute to the prevention of HAI and AMR at different levels. Microbiome research may offer innovative concepts for future prevention, whole genome sequencing could detect new modes of transmission and become an additional tool for effective public health epidemiology, antimicrobial surfaces might help to decrease the environment as source of transmission but continue to raise more questions than answers, and technological innovation may have a role in improving surveillance approaches and supporting best practice in hand hygiene.",

author = "Walter Zingg and Park, {Benjamin J.} and Julie Storr and Raheelah Ahmad and Carolyn Tarrant and Enrique Castro-Sanchez and Eli Perencevich and Andreas Widmer and Krause, {Karl Heinz} and Claire Kilpatrick and Sara Tomczyk and Benedetta Allegranzi and Denise Cardo and Didier Pittet and Mohamed Abbas and Antoine Andremont and Mike Bell and Michael Borg and Yehuda Carmeli and John Conly and Philippe Eggimann and Petra Gastmeier and Grayson, {M. Lindsay} and Stephan Harbarth and Marcela Hernandez and Loreen Herwaldt and Alison Holmes and Jernigan, {John A.} and Amy Kolwaite and Elaine Larson and Sarah Masson-Roy and Shaheen Mehtar and Marc Mendelson and Lin, {Ling Moi} and Andreea Moldovan and Dominique Monnet and Babacar Ndoye and Peter Nthumba and Folasade Ogunsola and Matthew Samore and Seto, {Wing Hong} and Arjun Srinivasan and Evelina Tacconelli and Maha Talaat and Villegas, {Maria Virginia} and Andreas Voss and Tim Walsh",

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doi = "10.1186/s13756-019-0538-y",

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T1 - Technology for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva IPC-Think Tank (Part 2)

AU - Zingg, Walter

AU - Park, Benjamin J.

AU - Storr, Julie

AU - Ahmad, Raheelah

AU - Tarrant, Carolyn

AU - Castro-Sanchez, Enrique

AU - Perencevich, Eli

AU - Widmer, Andreas

AU - Krause, Karl Heinz

AU - Kilpatrick, Claire

AU - Tomczyk, Sara

AU - Allegranzi, Benedetta

AU - Cardo, Denise

AU - Pittet, Didier

AU - Abbas, Mohamed

AU - Andremont, Antoine

AU - Bell, Mike

AU - Borg, Michael

AU - Carmeli, Yehuda

AU - Conly, John

AU - Eggimann, Philippe

AU - Gastmeier, Petra

AU - Grayson, M. Lindsay

AU - Harbarth, Stephan

AU - Hernandez, Marcela

AU - Herwaldt, Loreen

AU - Holmes, Alison

AU - Jernigan, John A.

AU - Kolwaite, Amy

AU - Larson, Elaine

AU - Masson-Roy, Sarah

AU - Mehtar, Shaheen

AU - Mendelson, Marc

AU - Lin, Ling Moi

AU - Moldovan, Andreea

AU - Monnet, Dominique

AU - Ndoye, Babacar

AU - Nthumba, Peter

AU - Ogunsola, Folasade

AU - Samore, Matthew

AU - Seto, Wing Hong

AU - Srinivasan, Arjun

AU - Tacconelli, Evelina

AU - Talaat, Maha

AU - Villegas, Maria Virginia

AU - Voss, Andreas

AU - Walsh, Tim

PY - 2019/5/22

Y1 - 2019/5/22

N2 - Background: The high burden of healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) is partially due to excessive antimicrobial use both in human and animal medicine worldwide. How can technology help to overcome challenges in infection prevention and control (IPC) and to prevent HAI and emerging AMR? Methods: In June 2017, 42 international experts convened in Geneva, Switzerland to discuss four potential domains of technology in IPC and AMR: 1) role and potential contribution of microbiome research; 2) whole genome sequencing; 3) effectiveness and benefit of antimicrobial environmental surfaces; and 4) future research in hand hygiene. Results: Research on the microbiome could expand understanding of antimicrobial use and also the role of probiotics or even faecal transplantation for therapeutic purposes. Whole genome sequencing will provide new insights in modes of transmission of infectious diseases. Although it is a powerful tool for public health epidemiology, some challenges with interpretation and costs still need to be addressed. The effectiveness and cost-effectiveness of antimicrobially coated or treated environmental high-touch surfaces requires further research before they can be recommended for routine use. Hand hygiene implementation can be advanced, where technological enhancement of surveillance, technique and compliance are coupled with reminders for healthcare professionals. Conclusions: The four domains of technological innovation contribute to the prevention of HAI and AMR at different levels. Microbiome research may offer innovative concepts for future prevention, whole genome sequencing could detect new modes of transmission and become an additional tool for effective public health epidemiology, antimicrobial surfaces might help to decrease the environment as source of transmission but continue to raise more questions than answers, and technological innovation may have a role in improving surveillance approaches and supporting best practice in hand hygiene.

AB - Background: The high burden of healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) is partially due to excessive antimicrobial use both in human and animal medicine worldwide. How can technology help to overcome challenges in infection prevention and control (IPC) and to prevent HAI and emerging AMR? Methods: In June 2017, 42 international experts convened in Geneva, Switzerland to discuss four potential domains of technology in IPC and AMR: 1) role and potential contribution of microbiome research; 2) whole genome sequencing; 3) effectiveness and benefit of antimicrobial environmental surfaces; and 4) future research in hand hygiene. Results: Research on the microbiome could expand understanding of antimicrobial use and also the role of probiotics or even faecal transplantation for therapeutic purposes. Whole genome sequencing will provide new insights in modes of transmission of infectious diseases. Although it is a powerful tool for public health epidemiology, some challenges with interpretation and costs still need to be addressed. The effectiveness and cost-effectiveness of antimicrobially coated or treated environmental high-touch surfaces requires further research before they can be recommended for routine use. Hand hygiene implementation can be advanced, where technological enhancement of surveillance, technique and compliance are coupled with reminders for healthcare professionals. Conclusions: The four domains of technological innovation contribute to the prevention of HAI and AMR at different levels. Microbiome research may offer innovative concepts for future prevention, whole genome sequencing could detect new modes of transmission and become an additional tool for effective public health epidemiology, antimicrobial surfaces might help to decrease the environment as source of transmission but continue to raise more questions than answers, and technological innovation may have a role in improving surveillance approaches and supporting best practice in hand hygiene.

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Technology for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva IPC-Think Tank (Part 2)

Abstract

Bibliographical note

Funding

ASJC Scopus Subject Areas

UN SDGs

Access to Document

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Cite this