Columbia University Irving Medical Center

Proyectos

Proyectos por año 1984 2009 2022 2023 2024 2028

• 17 No iniciado
• 704 Activo
• 2419 Terminado

Proyectos por año

Resultados de la búsqueda

• Activo

  Generating Humanized Lungs in Mice for Disease Modeling and Development of Personalized Medicine Therapies

  Mori, M. (PI)

  Congressionally Directed Medical Research Programs

  1/1/19 → …

  Proyecto

  • Disease Modeling 100%
  • Blastocyst 100%
  • Personalized Medicine 100%
  • Lung 100%
  • Diseases 100%

• 2019 Alfred Sloan award

  Sampat, B. N. (PI)

  Alfred P. Sloan Foundation

  1/1/19 → …

  Proyecto

  • Innovations 100%
  • Natural Language Processing 100%

• Identifying ALS Therapeutics Through Multiplexed Drug Discovery Technologies

  Chavez, A. (PI)

  Congressionally Directed Medical Research Programs

  1/1/19 → …

  Proyecto

  • Drug Discovery 100%
  • Amyotrophic Lateral Sclerosis 100%
  • Clinical Trial 66%
  • Disease Model 44%
  • Diseases 22%

• Precision detection and characterization of pediatric severe acute respiratory infection in Uganda

  Cummings, M. M.

  Thrasher Research Fund

  1/1/18 → …

  Proyecto

• Urology Care Foundation Award

  Lee, S. H.

  Urology Care Foundation

  1/1/18 → …

  Proyecto

• International Tremor Conference

  Kuo, S. H. & Louis, E. D.

  Parkinson's Foundation

  1/1/18 → …

  Proyecto

• T1-rho MRI Evaluation of Glenohumeral Cartilage After Instability Repair

  Anderson, F. & Jobin, C.

  Orthopaedic Research and Education Foundation

  1/1/18 → …

  Proyecto

• Expansion of the Focal Epileptic Network: Identifying Predictors and Therapeutic Targets

  Gelinas, J. (PI)

  Citizens United for Research in Epilepsy

  1/1/18 → …

  Proyecto

  • Focal Epilepsy 100%
  • Diseases 100%
  • Neuronal Activity 50%
  • Brain Areas 50%
  • Neural Network 50%

• Genetic Causes and Therapeutic Interventions in Vascular Malformations

  Shawber, C. (PI)

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Proyecto

  • Genetics 100%
  • Gene Mutation 100%
  • Vascular Anomaly 100%
  • Congenital Blood Vessel Malformation 100%
  • Exome Sequencing 60%

• Targeted Approach to Lung Repair and Regeneration in Alveolar Type II Cell Disease

  Dorrello, N. V. (PI)

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Proyecto

  • Alveolar Type II Cells 100%
  • Lung 100%
  • Diseases 100%
  • Regeneration 100%
  • Lung Disease 100%

• Endosomal Chemokine Receptor Signaling as Basis for Metastasis in Malignant Melanoma

  Thomsen, A. R. B. A. R. B. (PI)

  LEO Fondet

  1/1/18 → …

  Proyecto

  • Guanine Nucleotide Binding Protein 100%
  • Metastatic Carcinoma 100%
  • Chemokine Receptor 100%
  • Melanoma 100%
  • Cell Migration 100%

• Stein Professorship/Extension

  Zhang, X. (PI)

  Research to Prevent Blindness

  1/1/18 → …

  Proyecto

  • Molecular Interaction 100%
  • Eye Development 100%
  • Growth Factor 100%
  • Intended Function 100%

• Modeling bladder cancer metastasis using human patient-derived tumor organoids

  Shen, M. M. (PI)

  Bladder Cancer Advocacy Network

  1/1/18 → …

  Proyecto

  • Organoid 100%
  • Bladder Cancer 100%
  • Neoplasm 100%
  • Metastatic Carcinoma 100%
  • Metastasis 100%

• Addressing Treatment Resistance in Models of Lethal Prostate Cancer by Identifying Novel Targets for Drug Discovery

  Vasciaveo, A. (PI)

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Proyecto

  • Drug Discovery 100%
  • Prostate Cancer 100%
  • Neoplasm 40%
  • Cancer Research 20%
  • Tumor Cell 15%

• Fluorenone Drug for Treatment of Combat-Related Traumatic Optic Neuropathy

  Petrukhin, K. (PI)

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Proyecto

  • Optic Neuropathy 100%
  • Optic Nerve Disease 100%
  • Optic Nerve 61%
  • Traumatic Brain Injury 23%
  • Neurotrauma 23%

• Prebiotic Inulin to Limit Antimicrobial-Resistant Infections During Critical Illness: A Phase II Clinical Trial

  Freedberg, D. (PI)

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Proyecto

  • Critical Illness 100%
  • Antiinfective Agent 100%
  • Infection 100%
  • Clinical Trial 100%
  • Inulin 100%

• Training in cytogenetics for diagnosis and evaluation of hematologic diseases

  Hassan, J. J. (PI)

  American Society of Hematology

  1/1/18 → …

  Proyecto

  • Health Care Personnel 100%
  • Hospital 100%
  • Hematologist 100%
  • Diseases 100%
  • Health Care 100%

• Biodegradable Cationic Nanoparticles as a Push Chemodrug Carrier and a Pull cfDNA Scavenger Against Breast Cancer Metastasis

  Dalerba, P. D. (PI)

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Proyecto

  • Chemotherapy 100%
  • Nanoparticle 100%
  • Breast Cancer 100%
  • Metastasis 100%
  • Metastatic Breast Cancer 85%

• Targeting Mitochondrial Metabolism as a Key Vulnerability in Artemisinin-Resistant Plasmodium falciparum Malaria

  Fidock, D. A. (PI)

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Proyecto

  • Artemisinin 100%
  • Malaria Falciparum 100%
  • Mitochondrial Respiration 100%
  • Plasmodium falciparum 100%
  • K 13 40%

• Glucagonlike Peptide 2 (GLP-2) Analogues as a Novel Strategy for Prevention and Treatment of Graft-Versus-Host Disease

  Reshef, R. (PI)

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Proyecto

  • Graft Versus Host Reaction 100%
  • Graft-Versus-Host Disease 100%
  • Peptides 100%
  • Allogeneic Stem Cell Transplantation 38%
  • T Cell 38%

• Master Regulators Underlying Tumor-Microenvironment Interactions in Metastatic Prostate Cancer

  Shen, M. (PI), Califano, A. (CoPI), Abate-shen, C. (CoPI), Cambuli, F. (CoPI), Drake, C. (CoPI), Bates, S. (CoPI), Fojo, A. T. (CoPI) & Loda, M. (CoPI)

  Prostate Cancer Foundation

  1/1/18 → …

  Proyecto

  • Tumor Microenvironment 100%
  • Prostate Cancer 100%
  • Personalized Medicine 37%
  • Regulator Protein 37%
  • Neoplasm 37%

• Genetic Causes and Therapeutic Interventions in Vascular Malformations

  Wu, J. (PI)

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Proyecto

  • Genetics 100%
  • Gene Mutation 100%
  • Vascular Anomaly 100%
  • Congenital Blood Vessel Malformation 100%
  • Exome Sequencing 60%

• Endosomal Chemokine Receptor Signaling as Basis for Metastasis in Malignant Melanoma

  Thomsen, A. R. B. A. R. B. (PI)

  1/1/18 → …

  Proyecto

  • Guanine Nucleotide Binding Protein 100%
  • Metastatic Carcinoma 100%
  • Chemokine Receptor 100%
  • Melanoma 100%
  • Cell Migration 100%

• Metabolomics in Gulf War Illness: A Systems Biology Approach to Dissecting Mechanisms of Disease

  Lipkin, W. I. (PI)

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Proyecto

  • Biological Sciences 100%
  • Veterans 100%
  • Metabolomics 100%
  • Diseases 100%
  • Metabolite 50%

• Committee on Socioeconomic Status (CSES) Leadership Awards: Emerging and Distinguished Psychologists

  Brooks- Gunn, J. B. (PI)

  1/1/18 → …

  Proyecto

• ‘Auf- und Abstieg’: Ein Lebensspannen-Ansatz zu sozialem Status

  Weiss, D. (PI)

  1/1/18 → …

  Proyecto

  • Chlorpheniramine Maleate 100%
  • Zolpidem Tartrate 100%

• Genetic and Environmental Influences on the Pathogenesis of Parkinson's Disease: Young Adult Brain and Behavioral Risk Indicators

  Rauh, V. A. (PI)

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Proyecto

  • Young Adults 100%
  • Nervous System 100%
  • Environmental Influence 100%
  • Parkinson's Disease 100%
  • Pest Control 50%

• ‘Stepping Up and Stepping Down’: A Life-Span Approach to Social Status

  Weiss, D. (PI)

  Deutsche Forschungsgemeinschaft

  1/1/18 → …

  Proyecto

  • Chlorpheniramine Maleate 100%
  • Zolpidem Tartrate 100%
  • Lifespan 100%

• The wood age in Asia: Comparative perspectives on forest history in China

  Lee, J. S. (CoPI), Lander, B. G. (CoPI), Miller, I. M. (PI), Davis, B. C. (CoPI) & Sivaramakrishnan, K. (CoPI)

  American Council of Learned Societies

  1/1/18 → …

  Proyecto

  • Paleoecology 100%
  • Deforestation 100%

• Human ISG15 and USP18 Deficiencies Underlying Type I Interferonopathies

  Bogunovic, D. D. (PI) & Bogunovic, D. D. (CoPI)

  6/9/17 → 5/31/25

  Proyecto

  • Viral Disease 100%
  • Cytokine 50%
  • Inflammatory Disorder 50%
  • down Regulation 50%
  • Gene Product 50%

• ASH Minority Medical Student Award Program (MMSAP)

  Taborda, C.

  American Society of Hematology

  1/1/17 → …

  Proyecto

• Urology Care Foundation Award

  Lee, S. H.

  Urology Care Foundation

  1/1/17 → …

  Proyecto

• Medical Student Eye Research Fellowship

  Jauregui, R. R. (PI)

  Research to Prevent Blindness

  1/1/17 → …

  Proyecto

  • Research Grants 100%
  • Medical Student 100%
  • University 100%
  • Surgeon 100%

• Apathy and Negative Symptoms in Alzheimer's Disease: Investigation of the Proline*COMT Interaction for Symptom Targeting to Positively Impact Quality of Life

  Clelland, C. (PI)

  Congressionally Directed Medical Research Programs

  1/1/17 → …

  Proyecto

  • Methyltransferase 100%
  • Alzheimer's Disease 100%
  • Negative Syndrome 100%
  • Proline 100%
  • Negative Symptom 100%

• Identification of Effector and Suppressive T-Cell Clones in Graft-vs-Host Disease

  Reshef, R. (PI)

  Congressionally Directed Medical Research Programs

  1/1/17 → …

  Proyecto

  • T Cell 100%
  • Cell Clone 100%
  • Graft-Versus-Host Disease 100%
  • Graft Versus Host Reaction 100%
  • Allogeneic Stem Cell Transplantation 50%

• Study of Spinal Muscular Atrophy in a Human Neuromuscular Junction Three-Dimensional Optogenetic Model

  Fernandez Vila, O. (PI)

  Congressionally Directed Medical Research Programs

  1/1/17 → …

  Proyecto

  • Spinal Muscular Atrophy 100%
  • Optogenetics 100%
  • Neuromuscular Junction 100%
  • Motoneuron 100%
  • Synapse 42%

• The Role of Activation-Induced Cytidine Deaminase in Pesticide-Related Lymphomagenesis

  Leeman-neill, R. J. (PI)

  Congressionally Directed Medical Research Programs

  1/1/17 → …

  Proyecto

  • Activation Induced Cytidine Deaminase 100%
  • Cancer Prevention 100%
  • Cancer Genetics 100%
  • Environmental Exposure 100%
  • Public Health 100%

• Neural Crest Origin of TSC Tumors

  D'armiento, J. M. (PI)

  Congressionally Directed Medical Research Programs

  1/1/17 → …

  Proyecto

  • Neoplasm 100%
  • Neural Crest 100%
  • Tuberous Sclerosis 100%
  • HMGA2 36%
  • Stem Cell 36%

• Biased spatiotemporal dynamics of striatal circuits impact behavior in autism

  Costa, R. R. (PI)

  1/1/17 → …

  Proyecto

  • Behavior (Neuroscience) 100%
  • Compulsive Behavior 100%
  • Autism Spectrum Disorder 100%
  • Autism 100%
  • Basal Ganglia 75%

• Identification of Master Transcriptional Regulators of Neuroendocrine Differentiation in Prostate Cancer

  Cambuli, F. (PI)

  Congressionally Directed Medical Research Programs

  1/1/17 → …

  Proyecto

  • Prostate Cancer 100%
  • Cell Transdifferentiation 100%
  • Neuroendocrine Differentiation 100%
  • Transdifferentiation 100%
  • Prostate 83%

• Drug development of a novel PDE5 inhibitor for Alzheimer’s disease

  Fiorito, J. (PI)

  National Alzheimer's Association

  1/1/17 → …

  Proyecto

  • Phosphodiesterase V Inhibitor 100%
  • Alzheimer's Disease 100%
  • Nervous System Cell 100%
  • Phosphodiesterase V 100%
  • Drug Development 100%

• Attenuating Aß-driven hyperexcitability and tau spread

  Rodríguez, G. (PI)

  National Alzheimer's Association

  1/1/17 → …

  Proyecto

  • Tau Protein 100%
  • Nervous System Cell 100%
  • Alzheimer's Disease 100%
  • Beta Amyloid 50%
  • Cognitive Function 50%

• Axonal Transcription Factor Complexes in Alzheimer’s Disease

  Roque, C. G. (PI)

  National Alzheimer's Association

  1/1/17 → …

  Proyecto

  • Transcription Factors 100%
  • Nervous System Cell 100%
  • Alzheimer's Disease 100%
  • Axon 80%
  • Protein Complexes 60%

• NODDI vs. DTI metrics in predicting amyloid and tau pathology

  Gazes, Y. (PI)

  National Alzheimer's Association

  1/1/17 → …

  Proyecto

  • Tau 100%
  • Magnetic Resonance Imaging 100%
  • Alzheimer's Disease 100%
  • Amyloid Protein 100%
  • Diseases 100%

• Stopping tau propagation by receptor-mediated synaptic proteolysis

  Myeku, N. (PI)

  National Alzheimer's Association

  1/1/17 → …

  Proyecto

  • Proteolysis 100%
  • Tau Protein 100%
  • Nervous System Cell 100%
  • Receptor 100%
  • Tau 100%

• Alterations of TP53 mediate resistance to abiraterone in castration-resistant prostate cancer

  Zou, M. M. (PI) & Zou, M. M. (CoPI)

  Prostate Cancer Foundation

  4/15/16 → …

  Proyecto

  • Abiraterone 100%
  • Castration Resistant Prostate Cancer 100%
  • P53 100%
  • Prostate Cancer 75%
  • Protein P53 75%

• Parkinson's Foundation Research Centers 2016

  Kuo, S. H.

  Parkinson's Foundation

  1/1/16 → …

  Proyecto

• Parkinson's Foundation Research Centers 2016

  Sulzer, D.

  Parkinson's Foundation

  1/1/16 → …

  Proyecto

• Parkinson's Foundation Research Centers 2016

  Vonsattel, J. P. G.

  Parkinson's Foundation

  1/1/16 → …

  Proyecto

• Parkinson's Disease Penetrance in Obligate Carriers of SMPD1 Mutations

  Wise, A.

  Parkinson's Foundation

  1/1/16 → …

  Proyecto