Proyectos

Proyectos por año 1984 1984 1998 2012 2015 2019 2021 2022

• 3 Activo
• 18 Terminado

Proyectos por año

Resultados de la búsqueda

• Activo

  DISTINGUISHED INVESTIGATOR 2017

  Siegelbaum, S. A. (PI)

  Brain and Behavior Research Foundation

  1/1/17 → …

  Proyecto

  • Neurogenesis 100%
  • Patient Population 100%
  • Central Nervous System 100%

• Intracellular Ca++ Concentration and Organelle BehaviourDuring Regeneration and Synapse Formation

  Spira, M. (PI), Schacher, S. (CoPI) & Siegelbaum, S. A. (CoPI)

  United States-Israel Binational Science Foundation

  1/1/86 → …

  Proyecto

• Development, Maturation and Distribution of Sodium Channelsin Outgrowing Nerves

  Palti, Y. (PI), Meiri, H. (CoPI), Spitzer, N. (CoPI) & Siegelbaum, S. A. (CoPI)

  United States-Israel Binational Science Foundation

  1/1/84 → …

  Proyecto

• Terminado

  Hippocampal CA2 sharp wave ripple oscillations in neuropsychiatric disease

  Siegelbaum, S. A. (PI)

  National Institute of Mental Health

  12/10/21 → 10/31/22

  Proyecto

  • Dementia Praecox 100%
  • Brain Areas 50%
  • Hippocampus 50%
  • Social Behavior 50%
  • Electrical Brain Stimulation 50%

• Role of HCN1 channels in the function and malfunction of parvalbumin positive interneurons

  Siegelbaum, S. A. (PI)

  National Institute of Neurological Disorders and Stroke

  7/15/21 → 4/30/22

  Proyecto

  • Parvalbumin 100%
  • HCN1 100%
  • Interneuron 100%
  • In Vivo 15%
  • Brain Function 13%

• Regulation of social aggression through hippocampal CA2 inputs to lateral septum

  Siegelbaum, S. A. (PI)

  National Institute of Mental Health

  8/26/19 → 5/31/22

  Proyecto

  • Hippocampus 100%
  • Vasopressin 100%
  • Hypothalamus 50%
  • Behavior (Neuroscience) 50%
  • Social Interaction 50%

• Structural studies of HCN channels in health and disease

  Hendrickson, W. (CoPI), Hendrickson, W. (PI) & Siegelbaum, S. A. (CoPI)

  National Institute of Neurological Disorders and Stroke

  8/15/19 → 6/30/22

  Proyecto

  • HCN Channel 100%
  • Cryo-Electron Microscopy 75%
  • Cyclic Adenosine Monophosphate 75%
  • HCN4 75%
  • HCN1 75%

• The role of CA2 in epilepsy and social comorbidity

  Scharfman, H. (CoPI), Scharfman, H. (PI) & Siegelbaum, S. A. (CoPI)

  National Institute of Neurological Disorders and Stroke

  6/1/18 → 5/31/22

  Proyecto

  • Comorbidity 100%
  • Temporal Lobe Epilepsy 100%
  • Mouse 50%
  • Hippocampus 50%
  • Argipressin 16%

• The role of the hippocampal CA2 region in neuropsychiatric disease

  Siegelbaum, S. A. (PI)

  National Institute of Mental Health

  12/14/15 → 11/30/19

  Proyecto

  • Dementia Praecox 100%
  • Social Behavior 66%
  • Hippocampus 50%
  • Pervasive Developmental Disorder 50%
  • Schizophrenia Spectrum Disorder 33%

• Evaluating CA2 Neurons as Novel Targets in Epilepsy

  Scharfman, H. (PI) & Siegelbaum, S. A. (CoPI)

  National Institute of Neurological Disorders and Stroke

  9/1/15 → 8/31/17

  Proyecto

  • Mouse 100%
  • Hippocampus 100%
  • Amnesia 50%
  • Mouse Model 50%
  • Intractable Epilepsy 50%

• Prefrontal cortex and adolescent binge drinking: Role of HCN channels

  Harrison, N. (PI) & Siegelbaum, S. A. (CoPI)

  National Institute on Alcohol Abuse and Alcoholism

  2/15/15 → 1/31/21

  Proyecto

  • Prefrontal Cortex 100%
  • Cyclic Nucleotide 100%
  • Excitability 25%
  • HCN1 25%
  • Alcohol Abuse 8%

• Genetic targeting of hippocampal CA2 pyramidal neurons

  Siegelbaum, S. A. (PI)

  National Institute of Mental Health

  7/11/14 → 1/31/22

  Proyecto

  • Hippocampus 100%
  • Social Behavior 61%
  • Dementia Praecox 47%
  • Behavior (Neuroscience) 38%
  • Brain Areas 36%

• Regulation of HCN channel trafficking and function in the brain by TRIP8b

  Siegelbaum, S. A. (PI)

  National Institute of Neurological Disorders and Stroke

  8/1/12 → 7/31/13

  Proyecto

  • HCN1 100%
  • HCN Channel 100%
  • Dendrite 30%
  • Presynaptic Terminal 7%
  • Signaling Mechanism 7%

• Summer Program for Under Represented Students (SPURS)

  Siegelbaum, S. A. (PI)

  National Institute of Neurological Disorders and Stroke

  4/1/12 → 3/31/22

  Proyecto

  • Neuroscience 100%
  • Biomedical Research 100%
  • Journals 77%
  • Biological Sciences 54%
  • Medical Research 40%

• HCN1 channels in hippocampal function and spatial memory

  Siegelbaum, S. A. (PI)

  National Institute of Mental Health

  12/15/07 → 11/30/13

  Proyecto

  • HCN1 100%
  • Spatial Memory 100%
  • Dendrite 35%
  • Synaptic Plasticity 35%
  • Long-Term Potentiation 28%

• Regulation of HCN channel trafficking and function in the brain by TRIP8b

  Siegelbaum, S. A. (PI)

  National Institute of Neurological Disorders and Stroke

  4/1/98 → 7/31/17

  Proyecto

  • HCN1 100%
  • HCN Channel 100%
  • Cyclic Nucleotide-Gated Ion Channel 90%
  • Cyclic Nucleotide 58%
  • Electric Potential 58%

• CONFERENCE ON THE HIPPOCAMPUS

  Siegelbaum, S. A. (PI)

  National Institute of Neurological Disorders and Stroke

  3/1/98 → 2/28/99

  Proyecto

  • Common Interest 100%
  • Plenary Session 100%
  • Clinician 100%
  • Logopedics 100%
  • Hippocampus 100%

• PRESYNAPTIC PROTEINS IN TRANSMITTER RELEASE &SYNAPTIC PLASTICITY

  Siegelbaum, S. A. (PI)

  National Institute of Mental Health

  10/1/95 → 9/30/02

  Proyecto

  • Synaptic Plasticity 100%
  • Neurotransmitter Release 100%
  • Synaptophysin 100%
  • Synaptic Transmission 100%
  • Synaptic Vesicle 60%

• ION CHANNEL MODULATION IN CONTROL OF SYNAPTIC EFFICATION

  Siegelbaum, S. A. (PI)

  National Institute of Neurological Disorders and Stroke

  1/1/90 → 3/31/96

  Proyecto

  • Ion Channel 100%
  • Cyclic Adenosine Monophosphate 59%
  • FMRFamide 56%
  • Sensory Neuron 41%
  • Neurotransmitter Release 40%

• ION CHANNELS IN NORMAL AND ABNORMAL PACEMAKER ACTIVITY

  Siegelbaum, S. A. (PI)

  National Heart, Lung, and Blood Institute

  10/1/84 → 9/30/85

  Proyecto

• EFFECTS OF DRUGS ON SINGLE CHANNELS

  Siegelbaum, S. A. (PI)

  National Heart, Lung, and Blood Institute

  10/1/84 → 9/30/85

  Proyecto