Implication of a Mitochondrial Protein, ECSIT, in the Oxidative Stress Leading to Alzheimer's Disease

Alzheimer's disease is the world's most common cause of dementia, and oxidative stress has emerged as a key feature and possible cause of the disease. It appears early and can accelerate progression of the disease. However, only a few treatments directed towards preventing oxidative stress have produced positive results. With this project, we will study a promising novel mechanism causing oxidative stress in hopes of stimulating ideas for more efficient therapeutics.