Preclinical development of 3-hydroxypropaneamidine derivatives targeting Plasmodium falciparum

Pharmacology, Toxicology and Pharmaceutical Science

1. Plasmodium falciparum 100%
2. Antimalarial Agent 100%
3. Mouse Model 33%
4. Heme 33%
5. Antimalarial Activity 16%
6. SCID Mouse 16%
7. Cytotoxicity 16%
8. Malaria Vaccine 16%
9. Lead Compound 16%
10. Infection 16%
11. Hemozoin 16%
12. Tafenoquine 16%
13. Malaria Falciparum 16%
14. Benflumetol 16%
15. Combination Therapy 16%
16. Artemisinin Derivative 16%