Prevalence & Risk Factors of MGUS in a Black Sub-Saharan African Population

Multiple myeloma and its precursor, monoclonal gammopathy of undetermined significance (MGUS), both occur twice as often within Black populations compared to Whites. This suggests that racial disparities lie within the development of MGUS, and not progression to malignancy. Few studies have been conducted on MGUS within African cohorts. With the help of collaborators, Dr. Cicero is set to determine the prevalence of MGUS in a population of Black men and women in Eswatini. They will also assess the relationship between HIV status and MGUS by employing univariable and multivariable logistic regressions, controlling for age, gender, and socioeconomic status. They expect their results to be applicable not just to those in sub-Saharan Africa, but also to populations of African descent here in the US.