Quantification of plasma cholesterol and triglyceride levels in hypercholesterolemic subjects receiving ascorbic acid supplements

Nine hypercholesterolemic subjects were treated with oral ascorbic acid (4 g/day) for 2 months. The data demonstrate: no significant change in plasma cholesterol or triglyceride levels; no significant change in the cholesterol or triglyceride concentrations of the major lipoprotein classes; and the unexpected appearance of extra pre β bands lipoprotein electrophoresis by the end of the ascorbic acid treatment period.