A Therapeutic Approach to Synaptic Dysfunction in Alzheimer’s disease

Brain cells normally communicate with one another by sending and receiving chemical messages. These messages are transmitted through tiny spaces in between cells called synapses. Studies have found that in Alzheimer's disease, brain cells and synapses become damaged causing cell-to-cell communications to become hindered. These detrimental brain changes ultimately lead to losses in memory and other forms of cognition, a hallmark of Alzheimer's. However, it is not known exactly how dementia-related synaptic damage occurs.