The involvement of histone acetyl-transferases (HAT) in Alzheimer's Disease

Histones are proteins that help maintain the organization of DNA, which is an essential nucleic acid in cells that contains specific genetic information needed for any living organism to develop and function. Histones have also been shown to regulate the expression of genes. They can be modified by a biochemical process called acetylation, or the addition of a group of atoms called the acetyl group. Enzymes called histone acetyl-transferases (HATs) help carry out acetylation, which have been shown to affect the brain's ability to form memories