@article{a5d78df3f4f5467c8cf6b5f7df3ca1c3,
title = "A selective fluorescent probe for the detection of mercury (II) in aqueous media and its applications in living cells",
abstract = "In this Letter we present a new probe, 2-amino-3-hydroxy-2-(hydroxymethyl) propyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate (PMR), which can reversibly detect mercuric ions (Hg 2+) in HEPES buffer under physiological conditions. Possible interference with other analytes was examined. PMR displays a highly selective decrease of its fluorescence at 460 nm when it reacts with Hg 2+. Interestingly, the probe can also be used as a fluorescent turn-on sensor for biologically relevant thiols such as glutathione and cysteine. PMR can be used to determine mercury in living cells.",
author = "Olimpo Garc{\'i}a-Beltr{\'a}n and Natalia Mena and Berr{\'i}os, {Tania A.} and Castro, {Enrique A.} and Cassels, {Bruce K.} and N{\'u}{\~n}ez, {Marco T.} and Aliaga, {Margarita E.}",
note = "Funding Information: This work was supported by the Millennium Scientific Initiative (Grant P05-001-F ) and by Fondecyt Grant # 11090115 . The authors are grateful to Prof. Frank H. Quina for the use of spectroscopic facilities in the Institute of Chemistry and the USP Research Consortium for Photochemical Technology (NAP-PhotoTech), University of S{\~a}o Paulo, S{\~a}o Paulo, Brazil. ",
year = "2012",
month = nov,
day = "28",
doi = "10.1016/j.tetlet.2012.09.111",
language = "English",
volume = "53",
pages = "6598--6601",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "48",
}