A Systematic Framework to Rapidly Obtain Data on Patients with Cancer and COVID-19: CCC19 Governance, Protocol, and Quality Assurance

The COVID-19 and Cancer Consortium

Résultat de rechercheexamen par les pairs

24 Citations (Scopus)

Résumé

When the COVID-19 pandemic began, formal frameworks to collect data about affected patients were lacking. The COVID-19 and Cancer Consortium (CCC19) was formed to collect granular data on patients with cancer and COVID-19 at scale and as rapidly as possible. CCC19 has grown from five initial institutions to 125 institutions with >400 collaborators. More than 5,000 cases with complete baseline data have been accrued. Future directions include increased electronic health record integration for direct data ingestion, expansion to additional domestic and international sites, more intentional patient involvement, and granular analyses of still-unanswered questions related to cancer subtypes and treatments.

Langue d'origineEnglish
Pages (de-à)761-766
Nombre de pages6
JournalCancer Cell
Volume38
Numéro de publication6
DOI
Statut de publicationPublished - déc. 14 2020

Financement

The consortium would like to acknowledge the writing committee who drafted this manuscript: Dimpy P. Shah, MD, PhD; Sanjay Mishra, MS, PhD; and Jeremy L. Warner, MD, MS. The consortium would also like to acknowledge the early contributions of Dr. Nicole M. Kuderer, MD, and Dr. Donna R. Rivera, PharmD, MsC. We thank all members of the CCC19 steering committee: Toni K. Choueiri, MD; Petros Grivas, MD, PhD; Gilberto de Lima Lopes, Jr., MD, MBA; Corrie A. Painter, PhD; Solange Peters, MD, PhD; Brian I. Rini, MD; Dimpy P. Shah, MD, PhD; Michael A. Thompson, MD, PhD; and Jeremy L. Warner, MD, MS, for their invaluable guidance of the CCC19 consortium. This study was partly supported by grants from the American Cancer Society and Hope Foundation for Cancer Research ( MRSG-16-152-01-CCE ; to D.P.S.) and the National Cancer Institute ( P30 CA054174 to D.P.S.; P30 CA068485 to J.L.W. and S.M.; and U01 CA231840 to J.L.W.). REDCap is developed and supported by Vanderbilt Institute for Clinical and Translational Research grant support ( UL1 TR000445 from NCATS/NIH). The funding sources had no role in the writing of the manuscript or the decision to submit it for publication. The consortium would like to acknowledge the writing committee who drafted this manuscript: Dimpy P. Shah, MD, PhD; Sanjay Mishra, MS, PhD; and Jeremy L. Warner, MD, MS. The consortium would also like to acknowledge the early contributions of Dr. Nicole M. Kuderer, MD, and Dr. Donna R. Rivera, PharmD, MsC. We thank all members of the CCC19 steering committee: Toni K. Choueiri, MD; Petros Grivas, MD, PhD; Gilberto de Lima Lopes, Jr. MD, MBA; Corrie A. Painter, PhD; Solange Peters, MD, PhD; Brian I. Rini, MD; Dimpy P. Shah, MD, PhD; Michael A. Thompson, MD, PhD; and Jeremy L. Warner, MD, MS, for their invaluable guidance of the CCC19 consortium. This study was partly supported by grants from the American Cancer Society and Hope Foundation for Cancer Research (MRSG-16-152-01-CCE; to D.P.S.) and the National Cancer Institute (P30 CA054174 to D.P.S.; P30 CA068485 to J.L.W. and S.M.; and U01 CA231840 to J.L.W.). REDCap is developed and supported by Vanderbilt Institute for Clinical and Translational Research grant support (UL1 TR000445 from NCATS/NIH). The funding sources had no role in the writing of the manuscript or the decision to submit it for publication. J.L.W. reports having received personal fees from Westat and IBM Watson Health and equity in HemOnc.org LLC outside the submitted work.

Bailleurs de fondsNuméro du bailleur de fonds
Hope Foundation for Cancer ResearchMRSG-16-152-01-CCE
NCATS/NIH
National Institutes of Health
American Cancer Society
National Cancer InstituteP30CA177558, P30 CA068485, P30 CA054174, U01 CA231840
National Center for Advancing Translational Sciences
Vanderbilt Institute for Clinical and Translational ResearchUL1 TR000445
Korean Foundation for Cancer Research

    ASJC Scopus Subject Areas

    • Oncology
    • Cancer Research

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