Geographical distance predicts psychiatric treatment retention for Hispanic women with comorbid major depression and breast cancer

Ying Chen, John C. Markowitz, Carlos Blanco, Dawn L. Hershman, Joy T. Zhang, David J. Hellerstein

Résultat de rechercheexamen par les pairs

Résumé

Purpose: Depression is among the most common comorbid psychiatric disorders of patients with breast cancer. Depression decreases patient quality of life and, if untreated, can adversely affect cancer treatment. We sought to identify treatment barriers for women with breast cancer receiving psychotherapy for depression. Findings may help policy makers and researchers determine funding and design of future studies involving this population, especially in communities with high rates of health disparities. Methods: We used data from a randomized trial for women with breast cancer and current DSM-IV non-psychotic unipolar major depressive disorder (MDD). Patients were randomly assigned to 12 weeks of one of three psychotherapies and attrition was assessed by whether subjects completed 12 weekly treatment sessions. We used descriptive analyses and logistic regression to identify treatment barriers. R shiny was used to determine study patient residences. Results: Of 134 randomized patients, 84 (62.7%) were Hispanic. Fifty-nine patients (44%) either did not start or dropped out of treatment, 49 (83.1%) of them being Hispanic. Being a Hispanic woman, less educated, and geographically distant from treatment significantly predicted attrition. Single Hispanic mothers had significantly higher attrition risk than married and/or childless women. Conclusion: Identifying barriers to treatment is important to improve treatment adherence for patients with concurrent diagnoses of breast cancer and MDD, especially for traditionally underserved minorities. Additional support such as affordable tele-medicine, multi-language assistance, financial aid for transportation and child-care, and allocation of more funds to address some identified barriers deserve consideration to improve treatment adherence and outcomes.

Langue d'origineEnglish
Pages (de-à)249-256
Nombre de pages8
JournalBreast Cancer Research and Treatment
Volume205
Numéro de publication2
DOI
Statut de publicationPublished - juin 2024

Financement

John C. Markowitz: Reports receiving salary support from New York Psychiatric Institute; grant support from the National Institute of Mental Health, Department of Defense, and David Lynch Foundation. He receives minor book royalties for one of the study psychotherapies from American Psychiatric Publishing, Basic/Perseus Books, and Oxford University Press. David J. Hellerstein: Reports receiving salary support from New York Psychiatric Institute. He receives grant support from Compass Pathways, Relmada, Marinus, Intracellular Therapies, and Beckley Scientific, and from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (M Walker PI) and serves on the scientific advisory board for Reset Pharmaceuticals. He receives book royalties from Columbia University Press and Johns Hopkins University Press. Ying Chen, Carlos Blanco, Dawn L Hershman, Joy T. Zhang have not received any competing interests. The views and opinions expressed in this report are those of the authors and should not be construed to represent the views of any of the sponsoring organizations, agencies, or the US government.

Bailleurs de fondsNuméro du bailleur de fonds
U.S. Department of Defense
National Institute of Mental Health
National Institute of Arthritis and Musculoskeletal and Skin Diseases
David Lynch Foundation

    ASJC Scopus Subject Areas

    • Oncology
    • Cancer Research

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