HGF : c-met signaling inoligodendrocyte development and itsinhibition by CD82

  • Goldman, James (PI)

Project: Research project

Project Details

Description

Summary: Does a molecule called CD82 hold

a key to promoting myelin repair in MS?

Background: Myelin, the fatty substance that

surrounds and protects nerve fibers, is

attacked and destroyed in MS. The cells in the

brain that make myelin are called

oligodendrocytes. The brain contains a

population of “spare” immature

oligodendrocytes that need to mature in

order to produce and replace myelin. Finding

ways to encourage this maturation process is

likely to be important for stimulating myein

repair in the brains of people with MS.

StatusActive
Effective start/end date6/1/13 → …

Funding

  • National Multiple Sclerosis Society

ASJC Scopus Subject Areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)
  • Immunology and Microbiology(all)

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.