Novel nanostructured polymeric carriers to enable drug delivery for cardiovascular diseases

Javier O. Morales; Sabrina Sepulveda-Rivas; Felipe Oyarzun-Ampuero; Sergio Lavandero; Marcelo J. Kogan

doi:10.2174/1381612821666150901103556

Novel nanostructured polymeric carriers to enable drug delivery for cardiovascular diseases

Javier O. Morales, Sabrina Sepulveda-Rivas, Felipe Oyarzun-Ampuero, Sergio Lavandero, Marcelo J. Kogan

Universidad de Chile

Research output: Contribution to journal › Review article › peer-review

7 Citations (Scopus)

Abstract

Applications of polymeric nanotechnologies for enabling therapies for cardiovascular diseases have shown recent success. Both intravenous and oral administration have been investigated and achieved different degrees of development. While circulating polymeric nanostructured carriers are subjected to a number of interactions, smart nanoparticle design has enabled the formulation of active molecules to be delivered to specific targets for cardiovascular effects. This review aims at outlining the multiple factors that can affect the fate of polymeric nanostructured carriers in systemic circulation. With an understanding of these factors, the literature on the various polymeric nanostructured carriers is reviewed. Finally, the emerging uses of nanotechnology to formulate orally administered drugs for cardiovascular diseases are depicted.

Original language	English
Pages (from-to)	4276-4284
Number of pages	9
Journal	Current Pharmaceutical Design
Volume	21
Issue number	29
DOIs	https://doi.org/10.2174/1381612821666150901103556
Publication status	Published - Sept 1 2015

Bibliographical note

Publisher Copyright:
© 2015 Bentham Science Publishers.

ASJC Scopus Subject Areas

Pharmacology
Drug Discovery

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2174/1381612821666150901103556

Cite this

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AU - Sepulveda-Rivas, Sabrina

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AU - Lavandero, Sergio

AU - Kogan, Marcelo J.

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Novel nanostructured polymeric carriers to enable drug delivery for cardiovascular diseases

Abstract

Bibliographical note

ASJC Scopus Subject Areas

UN SDGs

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