Lack of effect of estrogen on rest and treadmill exercise in postmenopausal women without known cardiac disease

Millie Lee; Elsa Grace V. Giardina; Shunichi Homma; Marco R. DiTullio; Robert R. Sciacca

doi:10.1016/S0002-9149(97)00521-3

Lack of effect of estrogen on rest and treadmill exercise in postmenopausal women without known cardiac disease

Millie Lee, Elsa Grace V. Giardina, Shunichi Homma, Marco R. DiTullio, Robert R. Sciacca

School of Nursing

Producción científica › revisión exhaustiva

14 Citas (Scopus)

Resumen

To assess the peripheral vascular effects of estrogen in women without coronary disease, normal postmenopausal women (mean age 56 ± 8 years) participated in a randomized, crossover trial using treadmill exercise echocardiography, and received oral conjugated estrogen, 0.625 mg/day or underwent a drug-free period. There was no significant effect on heart rate, blood pressure, double product, left ventricular end-systolic and end- diastolic diameters, or electrocardiographic measures after estrogen. In contrast to the profound effects reported in patients with cardiac disease, oral estrogen in normal women does not bestow significant benefit on treadmill exercise echocardiographic variables at rest or during modest levels of exercise.

Idioma original	English
Páginas (desde-hasta)	793-797
Número de páginas	5
Publicación	American Journal of Cardiology
Volumen	80
N.º	6
DOI	https://doi.org/10.1016/S0002-9149(97)00521-3
Estado	Published - sep. 15 1997

Financiación

This study was supported in part by Grant HL-07406 from the Department of Health and Human Services, Bethesda, Maryland, Grant RR-00645 from the Research Resources Administration, Bethesda, Maryland, and a Grant from Linda and Peter Nisselson.

Financiadores	Número del financiador
Research Resources Administration
U.S. Department of Health and Human Services	RR-00645
National Center for Research Resources	M01RR000645

ASJC Scopus Subject Areas

Cardiology and Cardiovascular Medicine

Acceder al documento

10.1016/S0002-9149(97)00521-3

Otros archivos y enlaces

Citar esto

@article{5999d1d39cfc4384831f10bef8a57407,

title = "Lack of effect of estrogen on rest and treadmill exercise in postmenopausal women without known cardiac disease",

abstract = "To assess the peripheral vascular effects of estrogen in women without coronary disease, normal postmenopausal women (mean age 56 ± 8 years) participated in a randomized, crossover trial using treadmill exercise echocardiography, and received oral conjugated estrogen, 0.625 mg/day or underwent a drug-free period. There was no significant effect on heart rate, blood pressure, double product, left ventricular end-systolic and end- diastolic diameters, or electrocardiographic measures after estrogen. In contrast to the profound effects reported in patients with cardiac disease, oral estrogen in normal women does not bestow significant benefit on treadmill exercise echocardiographic variables at rest or during modest levels of exercise.",

author = "Millie Lee and Giardina, {Elsa Grace V.} and Shunichi Homma and DiTullio, {Marco R.} and Sciacca, {Robert R.}",

note = "Funding Information: This study was supported in part by Grant HL-07406 from the Department of Health and Human Services, Bethesda, Maryland, Grant RR-00645 from the Research Resources Administration, Bethesda, Maryland, and a Grant from Linda and Peter Nisselson. ",

year = "1997",

month = sep,

day = "15",

doi = "10.1016/S0002-9149(97)00521-3",

language = "English",

volume = "80",

pages = "793--797",

journal = "American Journal of Cardiology",

issn = "0002-9149",

publisher = "Elsevier Inc.",

number = "6",

}

TY - JOUR

T1 - Lack of effect of estrogen on rest and treadmill exercise in postmenopausal women without known cardiac disease

AU - Lee, Millie

AU - Giardina, Elsa Grace V.

AU - Homma, Shunichi

AU - DiTullio, Marco R.

AU - Sciacca, Robert R.

N1 - Funding Information: This study was supported in part by Grant HL-07406 from the Department of Health and Human Services, Bethesda, Maryland, Grant RR-00645 from the Research Resources Administration, Bethesda, Maryland, and a Grant from Linda and Peter Nisselson.

PY - 1997/9/15

Y1 - 1997/9/15

N2 - To assess the peripheral vascular effects of estrogen in women without coronary disease, normal postmenopausal women (mean age 56 ± 8 years) participated in a randomized, crossover trial using treadmill exercise echocardiography, and received oral conjugated estrogen, 0.625 mg/day or underwent a drug-free period. There was no significant effect on heart rate, blood pressure, double product, left ventricular end-systolic and end- diastolic diameters, or electrocardiographic measures after estrogen. In contrast to the profound effects reported in patients with cardiac disease, oral estrogen in normal women does not bestow significant benefit on treadmill exercise echocardiographic variables at rest or during modest levels of exercise.

AB - To assess the peripheral vascular effects of estrogen in women without coronary disease, normal postmenopausal women (mean age 56 ± 8 years) participated in a randomized, crossover trial using treadmill exercise echocardiography, and received oral conjugated estrogen, 0.625 mg/day or underwent a drug-free period. There was no significant effect on heart rate, blood pressure, double product, left ventricular end-systolic and end- diastolic diameters, or electrocardiographic measures after estrogen. In contrast to the profound effects reported in patients with cardiac disease, oral estrogen in normal women does not bestow significant benefit on treadmill exercise echocardiographic variables at rest or during modest levels of exercise.

UR - http://www.scopus.com/inward/record.url?scp=0031572288&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031572288&partnerID=8YFLogxK

U2 - 10.1016/S0002-9149(97)00521-3

DO - 10.1016/S0002-9149(97)00521-3

M3 - Article

C2 - 9315595

AN - SCOPUS:0031572288

SN - 0002-9149

VL - 80

SP - 793

EP - 797

JO - American Journal of Cardiology

JF - American Journal of Cardiology

IS - 6

ER -

Lack of effect of estrogen on rest and treadmill exercise in postmenopausal women without known cardiac disease

Resumen

Financiación

ASJC Scopus Subject Areas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto