Skeletal Stem Cells: A Basis for Orthopaedic Pathology and Tissue Repair

Ting Cong; Kyle W. Morse; Branden R. Sosa; Joseph M. Lane; Scott A. Rodeo; Matthew B. Greenblatt

doi:10.2106/JBJS.24.00905

Skeletal Stem Cells: A Basis for Orthopaedic Pathology and Tissue Repair

Ting Cong, Kyle W. Morse, Branden R. Sosa, Joseph M. Lane, Scott A. Rodeo, Matthew B. Greenblatt

Hospital for Special Surgery

Résultat de recherche › examen par les pairs

Résumé

Skeletal stem cells (SSCs) continually replenish mature cell populations to support skeletal homeostasis.SSCs repopulate by self-renewal, have multilineage potential, and are long-lived in vivo.SSCs express specific combinations of cell surface markers that reflect their lineage identity.SSCs adapt to their anatomic environment to support regional differences in skeletal behavior and pathology.

Langue d'origine	English
Pages (de-à)	418-426
Nombre de pages	9
Journal	Journal of Bone and Joint Surgery - Series A
Volume	107
Numéro de publication	4
DOI	https://doi.org/10.2106/JBJS.24.00905
Statut de publication	Published - févr. 19 2025

ASJC Scopus Subject Areas

Surgery
Orthopedics and Sports Medicine

Accès au document

10.2106/JBJS.24.00905

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Cong, T., Morse, K. W., Sosa, B. R., Lane, J. M., Rodeo, S. A., & Greenblatt, M. B. (2025). Skeletal Stem Cells: A Basis for Orthopaedic Pathology and Tissue Repair. Journal of Bone and Joint Surgery - Series A, 107(4), 418-426. https://doi.org/10.2106/JBJS.24.00905

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abstract = "Skeletal stem cells (SSCs) continually replenish mature cell populations to support skeletal homeostasis.SSCs repopulate by self-renewal, have multilineage potential, and are long-lived in vivo.SSCs express specific combinations of cell surface markers that reflect their lineage identity.SSCs adapt to their anatomic environment to support regional differences in skeletal behavior and pathology.",

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AU - Rodeo, Scott A.

AU - Greenblatt, Matthew B.

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AB - Skeletal stem cells (SSCs) continually replenish mature cell populations to support skeletal homeostasis.SSCs repopulate by self-renewal, have multilineage potential, and are long-lived in vivo.SSCs express specific combinations of cell surface markers that reflect their lineage identity.SSCs adapt to their anatomic environment to support regional differences in skeletal behavior and pathology.

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Skeletal Stem Cells: A Basis for Orthopaedic Pathology and Tissue Repair

Résumé

ASJC Scopus Subject Areas

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