Abstract
In a prospective cohort study, we examined clinical features in 250 nondemented patients with idiopathic Parkinson's disease (PD) and then evaluated their association with incident dementia during 5 years of follow-up. Seventy-four of the patients became demented. Odds ratios for incident dementia with PD were increased for the following: being older than 70 years of age (2.7; 1.4 to 5.5), having a PD rating scale score greater than 25 (3.0; 1.5 to 6.2), being depressed (2.7; 1.5 to 6.6), being confused or psychotic on levodopa (3.3; 1.3 to 8.7), or having facial masking as a presenting sign (6.1; 1.4 to 26.9).
Original language | English |
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Pages (from-to) | 1690-1692 |
Number of pages | 3 |
Journal | Neurology |
Volume | 43 |
Issue number | 9 |
Publication status | Published - Sept 1993 |
Funding
Funders | Funder number |
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National Institute on Aging | P50AG008702 |
ASJC Scopus Subject Areas
- Clinical Neurology
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Stern, Y., Marder, K., Tang, M. X., & Mayeux, R. (1993). Antecedent clinical features associated with dementia in Parkinson's disease. Neurology, 43(9), 1690-1692.