Antecedent clinical features associated with dementia in Parkinson's disease

Yaakov Stern, Karen Marder, Ming Xi Tang, Richard Mayeux

Producción científicarevisión exhaustiva

154 Citas (Scopus)

Resumen

In a prospective cohort study, we examined clinical features in 250 nondemented patients with idiopathic Parkinson's disease (PD) and then evaluated their association with incident dementia during 5 years of follow-up. Seventy-four of the patients became demented. Odds ratios for incident dementia with PD were increased for the following: being older than 70 years of age (2.7; 1.4 to 5.5), having a PD rating scale score greater than 25 (3.0; 1.5 to 6.2), being depressed (2.7; 1.5 to 6.6), being confused or psychotic on levodopa (3.3; 1.3 to 8.7), or having facial masking as a presenting sign (6.1; 1.4 to 26.9).

Idioma originalEnglish
Páginas (desde-hasta)1690-1692
Número de páginas3
PublicaciónNeurology
Volumen43
N.º9
EstadoPublished - sep. 1993

Financiación

FinanciadoresNúmero del financiador
National Institute on AgingP50AG008702

    ASJC Scopus Subject Areas

    • Clinical Neurology

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