Antecedent clinical features associated with dementia in Parkinson's disease

Yaakov Stern, Karen Marder, Ming Xi Tang, Richard Mayeux

Résultat de rechercheexamen par les pairs

154 Citations (Scopus)

Résumé

In a prospective cohort study, we examined clinical features in 250 nondemented patients with idiopathic Parkinson's disease (PD) and then evaluated their association with incident dementia during 5 years of follow-up. Seventy-four of the patients became demented. Odds ratios for incident dementia with PD were increased for the following: being older than 70 years of age (2.7; 1.4 to 5.5), having a PD rating scale score greater than 25 (3.0; 1.5 to 6.2), being depressed (2.7; 1.5 to 6.6), being confused or psychotic on levodopa (3.3; 1.3 to 8.7), or having facial masking as a presenting sign (6.1; 1.4 to 26.9).

Langue d'origineEnglish
Pages (de-à)1690-1692
Nombre de pages3
JournalNeurology
Volume43
Numéro de publication9
Statut de publicationPublished - sept. 1993

Financement

Bailleurs de fondsNuméro du bailleur de fonds
National Institute on AgingP50AG008702

    ASJC Scopus Subject Areas

    • Clinical Neurology

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    Citer

    Stern, Y., Marder, K., Tang, M. X., & Mayeux, R. (1993). Antecedent clinical features associated with dementia in Parkinson's disease. Neurology, 43(9), 1690-1692.