Immunostimulatory cancer-associated fibroblast subpopulations can predict immunotherapy response in head and neck cancer

  • Aleksandar Obradovic (Contributor)
  • Diana Graves (Contributor)
  • Michael Korrer (Contributor)
  • Yu Wang (Contributor)
  • Yaomin Xu (Contributor)
  • Adam Luginbuhl (Contributor)
  • Joseph M. Curry (Contributor)
  • Sohini Roy (Contributor)
  • Michael Gibson (Contributor)
  • Paula Hurley (Contributor)
  • Charles Drake (Contributor)
  • Andrea Califano (Contributor)
  • Young Kim (Contributor)

Dataset

Description

RNA-Sequencing Data Associated with the manuscript "Immunostimulatory cancer-associated fibroblast subpopulations can predict immunotherapy response in head and neck cancer." Includes integrated single-cell RNA-Sequencing data & VIPER inferred protein activity matrix uploaded as Seurat Objects with patient and cluster metadata included, as well as sub-clustered fibroblast Seurat object and spatial geomx data. Also includes bulk RNA-Sequencing datasets of responders vs non-responders to treatment and bulk RNA-Sequencing datasets of sorted fibroblast populations used for cluster phenotyping and ex vivo co-culture experiments.
Datos disponiblesdic. 15 2021
EditorMendeley Data

Citar esto